Aronson P J, Lorincz A L
Acta Derm Venereol. 1985;65(1):19-24.
Since acetylcholine is the main neurotransmitter of eccrine sweating, phosphatidylcholine ingestion might increase sweating. In 10 adults mid-palmar sweating was measured 12 hours after ingestion of a high and a low phosphatidylcholine supper. In a double blind, crossover study, mid-palmar sweating was measured in 11 consenting adults 12 hours after a low phosphatidylcholine supper taken with either lecithin or placebo. Five minutes after cleaning the palm and drying, sweat was captured in a quick-drying plastic film. The film was removed with cellophane tape and placed on a glass slide. Mean "droplet" diameter was measured by averaging the greatest diameter of 25 "droplets." Ten of 10 subjects (100%) produced more sweat with a high phosphatidylcholine meal than with a low one. Compared to placebo, 10 of 11 subjects (91%) given lecithin had significantly increased sweat secretion (p less than 0.01). It remains to be confirmed that this phosphatidylcholine-induced sweating increase is clinically significant.
由于乙酰胆碱是外泌汗腺出汗的主要神经递质，摄入磷脂酰胆碱可能会增加出汗量。在10名成年人中，分别在摄入高磷脂酰胆碱晚餐和低磷脂酰胆碱晚餐12小时后测量手掌中部的出汗量。在一项双盲交叉研究中，对11名自愿参与的成年人在摄入低磷脂酰胆碱晚餐并搭配卵磷脂或安慰剂12小时后测量手掌中部的出汗量。清洁手掌并擦干五分钟后，用速干塑料薄膜收集汗液。用透明胶带取下薄膜并放在载玻片上。通过平均25个“液滴”的最大直径来测量平均“液滴”直径。10名受试者中有10名（100%）摄入高磷脂酰胆碱餐时比摄入低磷脂酰胆碱餐时出汗更多。与安慰剂相比，11名接受卵磷脂的受试者中有10名（91%）的汗液分泌显著增加（p<0.01）。磷脂酰胆碱引起的出汗增加是否具有临床意义仍有待证实。
