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"Bad regenerators" die after spinal cord injury: insights from lampreys.

作者信息

Barreiro-Iglesias Antón

机构信息

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.

出版信息

Neural Regen Res. 2015 Jan;10(1):25-7. doi: 10.4103/1673-5374.150642.

DOI:10.4103/1673-5374.150642
PMID:25788909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4357105/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f7e/4357105/b69db75ce158/NRR-10-25-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f7e/4357105/b69db75ce158/NRR-10-25-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f7e/4357105/b69db75ce158/NRR-10-25-g001.jpg

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本文引用的文献

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Detection of activated caspase-8 in injured spinal axons by using fluorochrome-labeled inhibitors of caspases (FLICA).使用荧光染料标记的半胱天冬酶抑制剂（FLICA）检测受损脊髓轴突中活化的半胱天冬酶-8。
Methods Mol Biol. 2015;1254:329-39. doi: 10.1007/978-1-4939-2152-2_23.
2
Cannabinoid CB2 receptor (CB2R) stimulation delays rubrospinal mitochondrial-dependent degeneration and improves functional recovery after spinal cord hemisection by ERK1/2 inactivation.大麻素CB2受体（CB2R）刺激可延缓红核脊髓束线粒体依赖性变性，并通过ERK1/2失活改善脊髓半切术后的功能恢复。
Cell Death Dis. 2014 Sep 4;5(9):e1404. doi: 10.1038/cddis.2014.364.
3
吗啉代寡核苷酸研究揭示了调节七鳃鳗轴突再生的信号通路。
Neural Regen Res. 2022 Jul;17(7):1475-1477. doi: 10.4103/1673-5374.330597.
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Serotonin inhibits axonal regeneration of identifiable descending neurons after a complete spinal cord injury in lampreys.5-羟色胺抑制七鳃鳗全脊髓损伤后可识别的下行神经元的轴突再生。
Dis Model Mech. 2019 Feb 20;12(2):dmm037085. doi: 10.1242/dmm.037085.
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Regenerative capacity in the lamprey spinal cord is not altered after a repeated transection.七鳃鳗脊髓的再生能力在多次横切后不会改变。
PLoS One. 2019 Jan 30;14(1):e0204193. doi: 10.1371/journal.pone.0204193. eCollection 2019.
6
GABA promotes survival and axonal regeneration in identifiable descending neurons after spinal cord injury in larval lampreys.GABA 促进幼体七鳃鳗脊髓损伤后可识别的下行神经元的存活和轴突再生。
Cell Death Dis. 2018 Jun 28;9(6):663. doi: 10.1038/s41419-018-0704-9.
7
Role of Caspase-8 and Fas in Cell Death After Spinal Cord Injury.半胱天冬酶 -8 和 Fas 在脊髓损伤后细胞死亡中的作用
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[Lampreys as an animal model in regeneration studies after spinal cord injury].[七鳃鳗作为脊髓损伤后再生研究的动物模型]
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Delayed death of identified reticulospinal neurons after spinal cord injury in lampreys.七鳃鳗脊髓损伤后特定网状脊髓神经元的延迟死亡
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