Han Ian C, Scott Adrienne W
Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Maryland.
Retin Cases Brief Rep. 2015 Summer;9(3):242-4. doi: 10.1097/ICB.0000000000000149.
To report a case of presumed sterile endophthalmitis after intravitreal ocriplasmin injection.
Observational case report. Review of clinical examination, ocular imaging, and published literature.
A 67-year-old woman with early cataracts presented with decreased vision in the left eye related to vitreomacular adhesion. She was treated with intravitreal ocriplasmin injection and developed a severe anterior chamber inflammatory reaction in less than 24 hours after the injection. Inflammation responded completely to topical steroids alone, without topical or intravitreal antibiotics.
Patients treated with intravitreal ocriplasmin may develop an acute inflammatory reaction, which can be severe.
报告1例玻璃体内注射奥克纤溶酶后疑似无菌性眼内炎的病例。
观察性病例报告。回顾临床检查、眼部影像学检查及已发表的文献。
一名患有早期白内障的67岁女性因玻璃体黄斑粘连出现左眼视力下降。她接受了玻璃体内注射奥克纤溶酶治疗，并在注射后不到24小时出现严重的前房炎症反应。炎症仅通过局部使用类固醇完全消退，未使用局部或玻璃体内抗生素。
接受玻璃体内注射奥克纤溶酶治疗的患者可能会发生急性炎症反应，且可能较为严重。
