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通过右前开胸入路对八旬老人进行微创主动脉瓣置换术。

Minimally invasive aortic valve replacement in octogenarians performed via a right anterior thoracotomy approach.

作者信息

Krishna Rama K, Santana Orlando, Mihos Christos G, Pineda Andrés M, Weiss Ursula Keller, Lamelas Joseph

出版信息

J Heart Valve Dis. 2014 Nov;23(6):671-4.

Abstract

BACKGROUND AND AIM OF THE STUDY

A significant number of patients aged > or =80 years are denied aortic valve surgery due to the assumption of poor outcomes with surgery. The study aim was to evaluate the outcomes of minimally invasive aortic valve replacement (AVR), performed via a right anterior thoracotomy approach, in octogenarians.

METHODS

A retrospective review was conducted of all minimally invasive isolated AVRs in patients aged > or =80 years performed at the authors' institution between February 2009 and April 2014. The operative times, postoperative complications, hospital length of stay and mortality were analyzed.

RESULTS

A total of 255 consecutive patients (133 males, 122 females; mean age 83.5 +/- 3 years) was identified. The mean left ventricular ejection fraction was 57 +/- 10%, and 31 patients (12.2%) had prior cardiac surgery. The median predicted Society of Thoracic Surgeons mortality score was 3.2% (IQR 2.4-4.4%). Postoperatively, four patients (1.6%) had cerebrovascular accidents, 38 (14.9%) had prolonged ventilation, four (1.6%) required reoperation for bleeding, and eight (3.1%) had acute kidney injury. The median intensive care unit length of stay was 48.5 h (IQR 27-92 h) and the postoperative length of stay was 7 days (IQR 5-9 days). The 30-day mortality was 3.1% (n=8), and the combined end point of morbidity and mortality was 19.2% (n=49). The all-cause mortality at one and three years was 6.7%, and 10.2%, respectively.

CONCLUSION

Minimally invasive AVR in octogenarians, performed via a right anterior thoracotomy approach, is associated with a low morbidity and mortality. This applies to both primary or reoperative surgery.

摘要

研究背景与目的

相当一部分年龄≥80岁的患者因认为手术预后不佳而被拒绝接受主动脉瓣手术。本研究的目的是评估经右前外侧开胸入路进行的微创主动脉瓣置换术(AVR)在八旬老人中的手术效果。

方法

对2009年2月至2014年4月在作者所在机构为年龄≥80岁的患者进行的所有微创单纯AVR手术进行回顾性分析。分析手术时间、术后并发症、住院时间和死亡率。

结果

共确定了255例连续患者(133例男性,122例女性;平均年龄83.5±3岁)。平均左心室射血分数为57±10%,31例患者(12.2%)曾接受过心脏手术。胸外科医师协会预测死亡率中位数为3.2%(四分位间距2.4 - 4.4%)。术后,4例患者(1.6%)发生脑血管意外,38例(14.9%)需要延长通气时间,4例(1.6%)因出血需要再次手术,8例(3.1%)发生急性肾损伤。重症监护病房住院时间中位数为48.5小时(四分位间距27 - 92小时),术后住院时间为7天(四分位间距5 - 9天)。30天死亡率为3.1%(n = 8),发病率和死亡率的联合终点为19.2%(n = 49)。1年和3年的全因死亡率分别为6.7%和10.2%。

结论

经右前外侧开胸入路对八旬老人进行微创AVR手术,其发病率和死亡率较低。这适用于初次手术或再次手术。

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