Aviram Amir, Bardin Ron, Wiznitzer Arnon, Yogev Yariv, Hadar Eran
Helen Schneider Hospital for Women, Rabin Medical Center, Petah Tikva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Fetal Diagn Ther. 2015;38(3):205-11. doi: 10.1159/000375446. Epub 2015 Mar 12.
The aim of this study was to investigate whether midtrimester isolated short femur length is associated with pregnancy complications.
Retrospective analysis of pregnancies with a midtrimester femur length <5th percentile for gestational age compared to controls with a femur length ≥5th percentile. Outcome measures included hypertensive disorders, being small for gestational age, oligohydramnios and preterm delivery.
2,105 women were eligible for this study, 85 (3.45%) of whom were in the study group and 2,020 were controls. Birth weight <10th percentile for gestational age (OR 4.4, 95% CI 2.5-7.8), birth weight <3rd percentile for gestational age (OR 31.0, 95% CI 13.3-72.3) and severe preeclampsia (OR 6.3, 95% CI 1.4-28.6) were significantly associated with midtrimester isolated short femur length.
Midtrimester isolated short femur length is associated with higher rates of being small for gestational age and preeclampsia.
本研究旨在调查孕中期孤立性股骨长度短是否与妊娠并发症相关。
对孕中期股骨长度低于胎龄第5百分位数的妊娠进行回顾性分析，并与股骨长度≥第5百分位数的对照组进行比较。观察指标包括高血压疾病、小于胎龄儿、羊水过少和早产。
2105名女性符合本研究条件，其中85名（3.45%）在研究组，2020名是对照组。出生体重低于胎龄第10百分位数（比值比4.4，95%置信区间2.5 - 7.8）、出生体重低于胎龄第3百分位数（比值比31.0，95%置信区间13.3 - 72.3）和重度子痫前期（比值比6.3，95%置信区间1.4 - 28.6）与孕中期孤立性股骨长度短显著相关。
孕中期孤立性股骨长度短与小于胎龄儿和子痫前期的发生率较高相关。
