孕中期孤立性股骨短小作为不良妊娠结局的预测指标

Midtrimester Isolated Short Femur Length as a Predictor of Adverse Pregnancy Outcome.

作者信息

Aviram Amir, Bardin Ron, Wiznitzer Arnon, Yogev Yariv, Hadar Eran

机构信息

Helen Schneider Hospital for Women, Rabin Medical Center, Petah Tikva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Fetal Diagn Ther. 2015;38(3):205-11. doi: 10.1159/000375446. Epub 2015 Mar 12.

DOI:10.1159/000375446

PMID:25790839

Abstract

OBJECTIVE

The aim of this study was to investigate whether midtrimester isolated short femur length is associated with pregnancy complications.

STUDY DESIGN

Retrospective analysis of pregnancies with a midtrimester femur length <5th percentile for gestational age compared to controls with a femur length ≥5th percentile. Outcome measures included hypertensive disorders, being small for gestational age, oligohydramnios and preterm delivery.

RESULTS

2,105 women were eligible for this study, 85 (3.45%) of whom were in the study group and 2,020 were controls. Birth weight <10th percentile for gestational age (OR 4.4, 95% CI 2.5-7.8), birth weight <3rd percentile for gestational age (OR 31.0, 95% CI 13.3-72.3) and severe preeclampsia (OR 6.3, 95% CI 1.4-28.6) were significantly associated with midtrimester isolated short femur length.

CONCLUSIONS

Midtrimester isolated short femur length is associated with higher rates of being small for gestational age and preeclampsia.

摘要

目的

本研究旨在调查孕中期孤立性股骨长度短是否与妊娠并发症相关。

研究设计

对孕中期股骨长度低于胎龄第5百分位数的妊娠进行回顾性分析，并与股骨长度≥第5百分位数的对照组进行比较。观察指标包括高血压疾病、小于胎龄儿、羊水过少和早产。

结果

2105名女性符合本研究条件，其中85名（3.45%）在研究组，2020名是对照组。出生体重低于胎龄第10百分位数（比值比4.4，95%置信区间2.5 - 7.8）、出生体重低于胎龄第3百分位数（比值比31.0，95%置信区间13.3 - 72.3）和重度子痫前期（比值比6.3，95%置信区间1.4 - 28.6）与孕中期孤立性股骨长度短显著相关。