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术后胰瘘:外科医生的噩梦!基于详细文献综述的见解

Postoperative Pancreatic Fistula: A Surgeon's Nightmare! An Insight with a Detailed Literature Review.

作者信息

Seetharam Prasad, Rodrigues Gabriel Sunil

机构信息

Kasturba Medical College, Manipal University. Manipal, India.

出版信息

JOP. 2015 Mar 20;16(2):115-24. doi: 10.6092/1590-8577/2937.

DOI:10.6092/1590-8577/2937
PMID:25791544
Abstract

CONTEXT

Postoperative fistula formation is an important complication following pancreatic resections.

OBJECTIVE

A large volume of literature without uniform conclusions is available regarding various controversies about postoperative pancreatic fistulae. The term postoperative pancreatic fistula includes fistula resulting from any surgery involving pancreas, most commonly pancreaticoduodenectomy and distal pancreatectomy. In this review, we have tried to present a comprehensive account of postoperative pancreatic fistula with particular emphasis on important controversies clouding the subject.

METHODS

We performed MEDLINE literature search for relevant articles using the key words pancreas, pancreatic cancer, pancreatectomy, pancreatoduodenectomy, Whipple's operation, postoperative, complications, fistula, management and treatment in various combinations with the Boolean operators AND, OR and NOT.

CONCLUSIONS

Postoperative pancreatic fistula is a troublesome complication of pancreaticoduodenectomy. Although the risk factors for postoperative pancreatic fistula have been extensively described, none of the methods recommended for preventing postoperative pancreatic fistula have been conclusively proved to be effective. While endoscopic treatment and percutaneous treatment form important aspects of treatment of postoperative pancreatic fistula, surgery may be required for select cases.

摘要

背景

术后瘘形成是胰腺切除术后的一种重要并发症。

目的

关于术后胰瘘的各种争议,有大量文献但结论不一。术后胰瘘这一术语包括任何涉及胰腺手术导致的瘘,最常见的是胰十二指肠切除术和远端胰腺切除术。在本综述中,我们试图全面阐述术后胰瘘,特别强调围绕该主题的重要争议。

方法

我们使用关键词胰腺、胰腺癌、胰腺切除术、胰十二指肠切除术、惠普尔手术、术后、并发症、瘘、管理和治疗等,以各种组合方式并结合布尔运算符AND、OR和NOT,在MEDLINE数据库中检索相关文章。

结论

术后胰瘘是胰十二指肠切除术的一个棘手并发症。尽管术后胰瘘的危险因素已被广泛描述,但推荐的预防术后胰瘘的方法均未被确凿证明有效。虽然内镜治疗和经皮治疗是术后胰瘘治疗的重要方面,但某些病例可能需要手术治疗。

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Postoperative Pancreatic Fistula: A Surgeon's Nightmare! An Insight with a Detailed Literature Review.术后胰瘘:外科医生的噩梦!基于详细文献综述的见解
JOP. 2015 Mar 20;16(2):115-24. doi: 10.6092/1590-8577/2937.
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Postoperative pancreatic fistula.术后胰瘘。
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