Mohammadjafari Hamid, Barzin Maryam, Salehifar Ebrahim, Khademi Kord Mahnaz, Aalaee Abdolrasoule, Mohammadjafari Roghieh
Department of Pediatrics, Cellular and Molecular Research Center, Faculty of Medicine.
Department Of Radiology, Boalisina Hospital.
Iran J Pediatr. 2014 Feb;24(1):69-74. Epub 2014 Jan 1.
To determine epidemiologic and metabolic characteristics of renal stone in the northern Iran.
We prospectively analyzed demographic, clinical and metabolic findings in children less than 16 years old with renal stone revealed by ultrasonography from September 2003 to May 2012. Evaluations included serum and urine measurement of main elements predisposing patients to stone formation. Findings : 271 children (160 males) aged 2 months to 16-years (mean 30 months) were evaluated. 91 (33.6%) had a positive family history, abdominal discomfort (18.8%), UTI (11.8%) and hematuria (11.4%) were main presenting features. 45 children were diagnosed accidentally without any specific compliant. Nearly all (99%) stones lay in kidney., 35.1% had metabolic, 10% infective and 4.1% obstructive trends, 110 children had no definable etiology. Hypercalciuria (25.5%) hyperoxaluria (18.4%) and hypocitraturia (18.1%) were more frequent than uricosuria (8.5%) and cystinuria (3.1%)
Metabolic derangement plays significant role in stone formation in our area. Patients should be carefully evaluated considering this point of view.
确定伊朗北部肾结石的流行病学和代谢特征。
我们前瞻性分析了2003年9月至2012年5月间通过超声检查发现患有肾结石的16岁以下儿童的人口统计学、临床和代谢结果。评估包括对易导致患者形成结石的主要元素进行血清和尿液检测。结果：对271名年龄在2个月至16岁（平均30个月）的儿童（160名男性）进行了评估。91名（33.6%）有阳性家族史，主要表现为腹部不适（18.8%）、尿路感染（11.8%）和血尿（11.4%）。45名儿童是在无任何特定症状的情况下偶然被诊断出的。几乎所有（99%）的结石位于肾脏。35.1%有代谢性、1
