Balat Ayse, Kilic Beltinge Demircioglu, Aksu Bagdagul, Kara Mehtap Akbalik, Buyukcelik Mithat, Agbas Ayse, Eroglu Fehime Kara, Gungor Tulin, Alaygut Demet, Yildiz Nurdan, Bastug Funda, Atmis Bahriye, Melek Engin, Elmaci Midhat, Tulpar Sebahat, Pehlivanoglu Cemile, Doven Serra Surmeli, Comak Elif, Tabel Yilmaz, Gemici Atilla, Uysal Berfin, Ozzorlar Gamze Seval, Kuçuk Nuran, Delibas Ali, Ozcelik Gul, Goknar Nilufer, Dursun Ismail, Ertan Pelin, Ozunan Ipek Akil, Sonmez Ferah
Division of Pediatric Nephrology, School of Medicine, Gaziantep University, 27310, Gaziantep, Turkey.
Department of Pediatric Basic Sciences, Institute of Child Health, Istanbul University, Istanbul, Turkey.
Pediatr Nephrol. 2022 Feb;37(2):393-402. doi: 10.1007/s00467-021-05046-3. Epub 2021 Jul 31.
Children are one of the most vulnerable groups in conflict zones, especially those with chronic diseases. This study aimed to investigate kidney disease profiles and problems during follow-up in a population of Syrian refugee children residing in Turkey.
Syrian refugee children aged between 0 and 18 years were included in the study. Demographic data, diagnosis, particular interventions due to nephrological problems, and problems encountered during follow-up were obtained from all participating pediatric nephrology centers.
Data from 633 children from 22 pediatric nephrology centers were included. Mean age of the children was 94.8 ± 61.7 months and 375 were male (59%). 57.7% had parental consanguinity and 23.3% had a close relative(s) with kidney disease. The most common kidney diseases were congenital anomalies of the kidney and urinary tract (CAKUT) (31.0%), glomerular disease (19.9%), chronic kidney disease (CKD) (14.8%), and urolithiasis (10.7%). Frequent reasons for CAKUT were nonobstructive hydronephrosis (23.0%), vesico-ureteral reflux (18.4%), and neurogenic bladder (15.8%). The most common etiology of glomerular diseases was nephrotic syndrome (69%). Ninety-four children had CKD, and 58 children were on chronic dialysis. Six children had kidney transplantation. Surgical intervention was performed on 111 patients. The language barrier, lack of medical records, and frequent disruptions in periodic follow-ups were the main problems noted.
CAKUT, glomerular disease, and CKD were highly prevalent in Syrian refugee children. Knowing the frequency of chronic diseases and the problems encountered in refugees would facilitate better treatment options and preventive measures.
儿童是冲突地区最脆弱的群体之一，尤其是那些患有慢性病的儿童。本研究旨在调查居住在土耳其的叙利亚难民儿童群体在随访期间的肾脏疾病概况及问题。
本研究纳入了年龄在0至18岁之间的叙利亚难民儿童。从所有参与的儿科肾脏病中心获取人口统计学数据、诊断结果、因肾脏问题进行的特殊干预措施以及随访期间遇到的问题。
纳入了来自22个儿科肾脏病中心的633名儿童的数据。儿童的平均年龄为94.8±61.7个月，其中375名是男性（59%）。57.7%的儿童父母有血缘关系，23.3%的儿童有患肾脏疾病的近亲。最常见的肾脏疾病是先天性肾脏和尿路畸形（CAKUT）（31.0%）、肾小球疾病（19.9%）、慢性肾脏病（CKD）（14.8%）和尿路结石（10.7%）。CAKUT的常见原因是非梗阻性肾积水（23.0%）、膀胱输尿管反流（18.4%）和神经源性膀胱（15.8%）。肾小球疾病最常见的病因是肾病综合征（69%）。94名儿童患有CKD，58名儿童接受慢性透析。6名儿童接受了肾脏移植。111名患者接受了手术干预。主要问题包括语言障碍、缺乏病历以及定期随访频繁中断。
CAKUT、肾小球疾病和CKD在叙利亚难民儿童中高度流行。了解慢性病的发生率以及难民中遇到的问题将有助于制定更好的治疗方案和预防措施。
