Ezzati Atefeh, Batoei Fereshteh, Jafari Seyed-Ali, Kiyani Mohammad-Ali, Mahdavi-Shahri Naser, Ahanchian Hamid, Tehranian Shahrzad, Kianifar Hamid-Reza
Clinical Research Development Center, Ghaem Hospital.
Mashhad University of Medical Sciences.
Iran J Pediatr. 2014 Oct;24(5):609-16. Epub 2014 Sep 12.
It is believed that fingerprints and palm patterns may represent genetically determined congenital abnormalities in Cystic Fibrosis (CF). The main idea of this paper was to determine differences of fingerprints and palm patterns in CF and normal children.
Forty-six CF children (27 males, 19 females) and 341 (113 males, 228 females) healthy individuals were recruited for this study. Fingerprint patterns, Total ridge count (TRC) of each finger, a-b ridge count, and atd angles of all participants were recorded. Asymmetry of the right and left hand for each value was determined and dissimilarity in fingerprint patterns between homologous fingers was compared using Chi-square analysis, Mann-Whitney U test and Fisher's exact test.
There were significant differences in the mean TRC of the right digit IV (P=0.009), left digit III (P=0.02), left digit IV (P=0.03), and left digit V (P=0.03). Furthermore, we found significant differences in right atd angel (P=0.001), left atd angel (P=0.002), right a-b ridge (P=0.007) and left a-b ridge (P=0.001). In contrast, we found no significant differences in atd angle asymmetry, a-b ridge count asymmetry and pattern dissimilarity score between both groups (P>0.05).
Dermatoglyphic characteristics could be used as a supplementary diagnostic method in CF children.
人们认为指纹和掌纹可能代表囊性纤维化(CF)中由基因决定的先天性异常。本文的主要目的是确定CF患儿与正常儿童在指纹和掌纹方面的差异。
本研究招募了46名CF患儿(27名男性,19名女性)和341名健康个体(113名男性,228名女性)。记录了所有参与者的指纹模式、每个手指的总嵴数(TRC)、a - b嵴数以及atd角。确定了每个值的左右手不对称性,并使用卡方分析、曼 - 惠特尼U检验和费舍尔精确检验比较了同源手指之间指纹模式的差异。
右手无名指(P = 0.009)、左手食指(P = 0.02)、左手无名指(P = 0.03)和左手小指(P = 0.03)的平均TRC存在显著差异。此外,我们发现右atd角(P = 0.001)、左atd角(P = 0.002)、右a - b嵴(P = 0.007)和左a - b嵴(P = 0.001)存在显著差异。相比之下,两组之间在atd角不对称性、a - b嵴数不对称性和模式差异得分方面没有显著差异(P>0.05)。
皮纹特征可作为CF患儿的辅助诊断方法。