一种人类免疫缺陷病毒的特洛伊木马。
A trojan horse for human immunodeficiency virus.
作者信息
Catuogno Silvia, Esposito Carla Lucia, de Franciscis Vittorio
机构信息
Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, 80145 Naples, Italy.
Istituto di Endocrinologia ed Oncologia Sperimentale, CNR, 80145 Naples, Italy.
出版信息
Chem Biol. 2015 Mar 19;22(3):313-4. doi: 10.1016/j.chembiol.2015.03.002.
Abstract
In this issue of Chemistry & Biology, Zhou et al. demonstrate the possibility of effective multiple targeting of HIV infection by using a multifunctional molecule in which an anti-CCR5 receptor aptamer (G-3) is conjugated to an anti-TNPO3 siRNA.
摘要
在本期《化学与生物学》中，周等人证明了通过使用一种多功能分子有效多重靶向HIV感染的可能性，该分子中抗CCR5受体适配体（G-3）与抗TNPO3小干扰RNA偶联。
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