Chong Catherine D, Schwedt Todd J
Department of Neurology, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA,
Curr Pain Headache Rep. 2015 May;19(5):485. doi: 10.1007/s11916-015-0485-0.
Over 2 million people are diagnosed with concussion each year in the USA, resulting in substantial individual and societal burdens. Although 'routine' clinical neuroimaging is useful for the diagnosis of more severe forms of traumatic brain injury, it is insensitive for detecting pathology associated with concussion. Diffusion tensor imaging (DTI) and blood-oxygenation-level-dependent (BOLD) resting-state functional connectivity magnetic resonance imaging (rs-fMRI) are techniques that allow for investigation of brain structural and functional connectivity patterns. DTI and rs-fMRI may be more sensitive than routine neuroimaging for detecting brain sequelae of concussion. This review summarizes recent DTI and rs-fMRI findings of altered structural and functional connectivity patterns in concussed patients.
在美国，每年有超过200万人被诊断为脑震荡，这给个人和社会带来了沉重负担。尽管“常规”临床神经影像学对诊断更严重形式的创伤性脑损伤很有用，但它对检测与脑震荡相关的病理情况并不敏感。扩散张量成像（DTI）和血氧水平依赖（BOLD）静息态功能连接磁共振成像（rs-fMRI）是用于研究脑结构和功能连接模式的技术。DTI和rs-fMRI在检测脑震荡后的脑后遗症方面可能比常规神经影像学更敏感。本综述总结了近期关于脑震荡患者结构和功能连接模式改变的DTI和rs-fMRI研究结果。
