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持续性脑震荡后症状(PPCS)青少年中抑郁、焦虑和自杀意念的患病率及其危险因素。

Prevalence and risk factors for depression, anxiety and suicidal ideation in youth with persistent post-concussive symptoms (PPCS).

机构信息

Center for Child Health, Behavior and Development, Seattle Children's Research Institute, Seattle WA, USA.

Department of Pediatrics, University of Washington Seattle, Washington, USA.

出版信息

Brain Inj. 2021 Nov 10;35(12-13):1637-1644. doi: 10.1080/02699052.2021.2008490. Epub 2021 Nov 28.

Abstract

To assess the prevalence and risk factors for emotional distress in youth with persistent post-concussive symptoms (PPCS) greater than one month. We used baseline data from an intervention study for youth with PPCS, utilizing Poisson regression to examine factors associated with exceeding clinical cut-points on measures of depression, anxiety, self-harm and suicidal ideation. Predictors included: age, sex, socioeconomic status, mental health history, duration of concussion symptoms, history of prior concussion, trauma history and sleep quality. The sample included 200 youth with PPCS, (mean 14.7 SD 1.7 years, 82% white, 62% female). Forty percent reported clinically significant depressive symptoms, 25% anxiety, 14% thoughts of self-harm and 8% thoughts of suicide. History of depression was associated with 3-fold higher risk for thoughts of self-harm (95% CI:1.82-6.99) and 6-fold higher risk for suicidal ideation (95% CI:1.74-24.46). Better sleep quality was associated with lower risk for all outcomes. History of prior concussion and duration of PPCS were not significantly associated with any outcomes. Suicidal thoughts are common post-concussion, and history of depression is a strong risk factor. Tailored interventions may be needed to address mental health in this population.

摘要

为了评估持续脑震荡后症状(PPCS)超过一个月的青少年情绪困扰的患病率和风险因素。我们使用了针对 PPCS 青少年的干预研究的基线数据,利用泊松回归来检查与超过抑郁、焦虑、自残和自杀意念测量标准的因素相关。预测因素包括:年龄、性别、社会经济地位、心理健康史、脑震荡症状持续时间、既往脑震荡史、创伤史和睡眠质量。样本包括 200 名患有 PPCS 的青少年,(平均年龄 14.7 标准差 1.7 岁,82%为白人,62%为女性)。40%报告有临床显著的抑郁症状,25%有焦虑症状,14%有自残念头,8%有自杀念头。抑郁史与自残念头的风险增加 3 倍(95%CI:1.82-6.99)和自杀意念的风险增加 6 倍(95%CI:1.74-24.46)相关。睡眠质量较好与所有结果的风险降低相关。既往脑震荡史和 PPCS 持续时间与任何结果均无显著相关性。脑震荡后自杀念头很常见,抑郁史是一个很强的风险因素。可能需要针对该人群的专门干预措施来解决心理健康问题。

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