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针对该流行病:儿科创伤性脑损伤诊所的干预措施和随访是必要的。

Targeting the Epidemic: Interventions and Follow-up Are Necessary in the Pediatric Traumatic Brain Injury Clinic.

作者信息

Choe M C, Valino H, Fischer J, Zeiger M, Breault J, McArthur D L, Leung M, Madikians A, Yudovin S, Lerner J T, Giza C C

机构信息

UCLA Brain Injury Research Center, Department of Neurosurgery, Los Angeles, CA, USA Division of Pediatric Neurology, David Geffen School of Medicine at UCLA and Mattel Children's Hospital - UCLA, Los Angeles, CA, USA Both authors contributed equally to the article.

University of California Davis School of Medicine, Los Angeles, CA, USA Both authors contributed equally to the article.

出版信息

J Child Neurol. 2016 Jan;31(1):109-15. doi: 10.1177/0883073815572685. Epub 2015 Mar 20.

DOI:10.1177/0883073815572685
PMID:25795464
Abstract

Traumatic brain injury is a major public health problem in the pediatric population. Previously, management was acute emergency department/primary care evaluation with follow-up by primary care. However, persistent symptoms after traumatic brain injury are common, and many do not have access to a specialized traumatic brain injury clinic to manage chronic issues. The goal of this study was to determine the factors related to outcomes, and identify the interventions provided in this subspecialty clinic. Data were extracted from medical records of 151 retrospective and 403 prospective patients. Relationships between sequelae, injury characteristics, and clinical interventions were analyzed. Most patients returning to clinic were not fully recovered from their injury. Headaches were more common after milder injuries, and seizures were more common after severe. The majority of patients received clinical intervention. The presence of persistent sequelae for traumatic brain injury patients can be evaluated and managed by a specialty concussion/traumatic brain injury clinic ensuring that medical needs are met.

摘要

创伤性脑损伤是儿科人群中的一个主要公共卫生问题。以前,管理方式是在急诊科/初级保健机构进行急性评估,随后由初级保健机构进行随访。然而,创伤性脑损伤后持续出现症状很常见,而且许多患者无法获得专门的创伤性脑损伤诊所来处理慢性问题。本研究的目的是确定与预后相关的因素,并确定该亚专科诊所提供的干预措施。数据从151例回顾性患者和403例前瞻性患者的病历中提取。分析了后遗症、损伤特征和临床干预之间的关系。大多数复诊患者尚未从损伤中完全康复。较轻损伤后头痛更常见,严重损伤后癫痫更常见。大多数患者接受了临床干预。创伤性脑损伤患者持续性后遗症的情况可由专科脑震荡/创伤性脑损伤诊所进行评估和管理,以确保满足医疗需求。

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Progesterone treatment following traumatic brain injury in the 11-day-old rat attenuates cognitive deficits and neuronal hyperexcitability in adolescence.11 日龄大鼠创伤性脑损伤后孕酮治疗可减轻青春期认知功能障碍和神经元过度兴奋。
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