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眼眶肿瘤揭示系统性结节病。

Orbital tumor revealing a systemic sarcoidosis.

作者信息

Hannanachi Sassi Samia, Dhouib Rim, Kanchal Fatma, Doghri Raoudha, Boujelbene Nadia, Bouguila Hedi, Mrad Karima

机构信息

Department of Pathology, Salah Azaeiz Institute, Bab Saadoun, 1006 Tunis, Tunisia.

Department of Ophthalmology, Hedi Rais Institute of Ophthalmology, Bab Saadoun, 1006 Tunis, Tunisia.

出版信息

Acta Med Iran. 2015;53(3):195-7.

Abstract

Ocular involvement is seen in approximately 25% of patients with sarcoidosis. Uveitis is the most common ocular manifestation, but sarcoidosis may involve any part of the eye. Orbital manifestations of sarcoidosis are uncommon with few series in the literature. A 65-year-old woman presented with redness of the right eye and painless, unilateral eyelid swelling. Orbital scanning revealed mass infiltrating the soft tissue of the inferior right orbital quadrant. Biopsy results showed nodular, noncaseating granulomas consistent with sarcoidosis. The complete systemic workup revealed systemic manifestations of sarcoidosis at the time of examination with hilar and mediastinal lymphadenopathies noted on CT scan. The orbital surgical treatment was followed by systemic prednisone therapy with good response. Although rare, orbital sarcoidosis must be considered in the evaluation of orbital tumors in elderly patients. A search for systemic findings should be undertaken and appropriate therapy should be instituted.

摘要

结节病患者中约25%会出现眼部受累。葡萄膜炎是最常见的眼部表现,但结节病可能累及眼部的任何部位。结节病的眼眶表现并不常见,文献中相关病例系列较少。一名65岁女性出现右眼发红和无痛性单侧眼睑肿胀。眼眶扫描显示有肿物浸润右下象限眼眶软组织。活检结果显示为结节状、非干酪样肉芽肿,符合结节病表现。全面的全身检查发现,检查时存在结节病的全身表现,CT扫描显示肺门和纵隔淋巴结肿大。眼眶手术治疗后进行全身泼尼松治疗,反应良好。尽管罕见,但在评估老年患者的眼眶肿瘤时必须考虑眼眶结节病。应进行全身检查并采取适当的治疗措施。

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