Krzesinski F, Cuppens B, Gerard C, Delhez A, Nogue A, Ghuysen A, D'Orio V D
Rev Med Liege. 2014 Oct;69(10):531-5.
Chronic consumption of soda energizing caffeine has known a growing success. Its deleterious effects, however, are often ignored. We report a case of tetraparesis associated with chronic excessive consumption of cola. The development of muscle weakness is variable, resulting from a hyperpolarization of excitable membranes. The outcome is most often favorable after potassium supplementation and interruption of the offending beverage consumption. The mechanisms involved are multiple and involve both a leakage of fecal and urinary potassium and a potassium entry into the intracellular compartment. Other mechanisms related to caffeine are also involved. It therefore appears mandatory to assess the consumption of such beverages in the presence of hypokalemia and muscle weakness.
长期饮用含能提神咖啡因的汽水越来越流行。然而,其有害影响却常常被忽视。我们报告一例与长期过量饮用可乐相关的四肢轻瘫病例。肌肉无力的发展情况各不相同,是由可兴奋膜的超极化引起的。补充钾并停止饮用有害饮料后,结果通常是良好的。涉及的机制是多方面的,包括粪便和尿液中钾的流失以及钾进入细胞内区室。还涉及与咖啡因相关的其他机制。因此,在出现低钾血症和肌肉无力的情况下,评估此类饮料的摄入量显得尤为必要。