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炎症性肠病患者血栓栓塞的预防与治疗

[Prevention and treatment of thromboembolism in patients with inflammatory bowel disease].

作者信息

Park Jae Jun

机构信息

Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Korean J Gastroenterol. 2015 Mar;65(3):151-8. doi: 10.4166/kjg.2015.65.3.151.

DOI:10.4166/kjg.2015.65.3.151
PMID:25797378
Abstract

Although inflammatory bowel disease (IBD) is a chronic disorder that mainly affects the gastrointestinal tract, extraintestinal complications can occur in IBD patients. Among many extraintestinal complications, venous thromboembolism (VTE) is particularly a feared complication due to its significant morbidity and mortality. IBD patients have about 2 to 3 fold higher risk of developing VTE compared with the general population, and the current management guidelines for IBD patients propose recommendations for the prevention of VTE. This review aims to summarize clinical characteristics of VTE in IBD patients and to outline strategies for preventing and treating VTE in these patients.

摘要

尽管炎症性肠病(IBD)是一种主要影响胃肠道的慢性疾病,但IBD患者可能会出现肠外并发症。在众多肠外并发症中,静脉血栓栓塞(VTE)因其较高的发病率和死亡率而成为特别令人担忧的并发症。与普通人群相比,IBD患者发生VTE的风险高出约2至3倍,目前IBD患者的管理指南提出了预防VTE的建议。本综述旨在总结IBD患者VTE的临床特征,并概述这些患者预防和治疗VTE的策略。

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