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161例神经根型颈椎病患者椎间盘内注射类固醇/选择性神经根阻滞的治疗结果

Treatment outcomes of intradiscal steroid injection/selective nerve root block for 161 patients with cervical radiculopathy.

作者信息

Ito Keigo, Yukawa Yasutsugu, Machino Masaaki, Inoue Taro, Ouchida Jun, Tomita Keisuke, Kato Fumihiko

机构信息

Department of Orthopedic Surgery, Chubu Rosai Hospital, Nagoya, Japan.

出版信息

Nagoya J Med Sci. 2015 Feb;77(1-2):213-9.

PMID:25797986
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4361523/
Abstract

Patients with cervical radiculopathy (CR) were treated with intradiscal injection of steroids (IDIS) and/or selective nerve root block (SNRB) at our hospital. We retrospectively report the outcomes of these nonsurgical treatments for CR. 161 patients who were followed up for >2months were enrolled in this study. Patients' clinical manifestations were classified as arm pain, arm numbness, neck and/or scapular pain, and arm paralysis. Improvement in each manifestation was classified as "disappeared," "improved," "poor," or "worsened." Responses of "disappeared" or "improved" manifestations suggested treatment effectiveness. Final clinical outcomes were evaluated using the Odom criteria. Changes in herniated disc size were evaluated by comparing the initial and final MRI scans. On the basis of these changes, the patients were divided into regression, no-change, or progression groups. We investigated the relationship between the Odom criteria and changes observed on MRI. Effectiveness rates were 89% for arm pain, 77% for arm numbness, 82% for neck and/or scapular pain, and 76% for arm paralysis. In total, 91 patients underwent repeated MRI. In 56 patients (62%), the size of the herniated disc decreased, but 31 patients (34%) exhibited no change in disc size. The regression group showed significantly better Odom criteria results than the no-change group. In conclusion, IDIS and SNRB for CR are not widely performed. However, other extremely effective therapies that can rapidly improve neuralgia should be considered before surgery.

摘要

我院对颈椎神经根病(CR)患者采用椎间盘内注射类固醇(IDIS)和/或选择性神经根阻滞(SNRB)进行治疗。我们回顾性报告这些CR非手术治疗的结果。本研究纳入了161例随访时间超过2个月的患者。患者的临床表现分为手臂疼痛、手臂麻木、颈部和/或肩胛疼痛以及手臂麻痹。每种表现的改善情况分为“消失”“改善”“差”或“恶化”。“消失”或“改善”的表现提示治疗有效。最终临床结果采用奥多姆标准进行评估。通过比较初始和最终的MRI扫描评估椎间盘大小的变化。根据这些变化,将患者分为缩小、不变或进展组。我们研究了奥多姆标准与MRI观察到的变化之间的关系。手臂疼痛的有效率为89%,手臂麻木为77%,颈部和/或肩胛疼痛为82%,手臂麻痹为76%。共有91例患者接受了重复MRI检查。56例患者(62%)椎间盘大小缩小,但31例患者(34%)椎间盘大小无变化。缩小组的奥多姆标准结果明显优于不变组。总之,CR的IDIS和SNRB治疗未广泛开展。然而,在手术前应考虑其他能迅速改善神经痛的极其有效的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/438c/4361523/225aa5451f09/2186-3326-77-0213-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/438c/4361523/d7737323c9ab/2186-3326-77-0213-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/438c/4361523/5dbff2a8dae6/2186-3326-77-0213-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/438c/4361523/225aa5451f09/2186-3326-77-0213-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/438c/4361523/d7737323c9ab/2186-3326-77-0213-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/438c/4361523/5dbff2a8dae6/2186-3326-77-0213-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/438c/4361523/225aa5451f09/2186-3326-77-0213-g003.jpg

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