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伊拉克和阿富汗美军退伍军人中健康士兵效应的侵蚀。

Erosion of the healthy soldier effect in veterans of US military service in Iraq and Afghanistan.

机构信息

South Texas Veterans Health Care System, 7400 Merton Minter Blvd, San Antonio, Texas USA ; Department of Medicine, Division of Hospital Medicine, University of Texas Health Science Center, San Antonio, Texas USA.

Department of Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, Texas USA.

出版信息

Popul Health Metr. 2015 Mar 18;13:8. doi: 10.1186/s12963-015-0040-6. eCollection 2015.

Abstract

BACKGROUND

This research explores the healthy soldier effect (HSE) - a lower mortality risk among veterans relative to the general population-in United States (US) veterans deployed in support of operations in Iraq and Afghanistan (OEF/OIF/OND). While a HSE has been affirmed in other OEF/OIF/OND populations, US veterans of OEF/OIF/OND have not been systematically studied.

METHODS

Using US Department of Veterans Affairs (VA) administrative data, we identified veterans who (1) had been deployed in support of OEF/OIF/OND between 2002 and 2011 and (2) were enrolled in the VA health care system. We divided the VA population into VA health care utilizers and non-utilizers. We obtained Department of Defense (DOD) administrative data on the OEF/OIF/OND population and obtained VA and DOD mortality data excluding combat deaths from the analyses. Indirect standardization was used to compare VA and DOD cohorts to the US population using total population at risk to compute the Standardized Mortality Ratio (SMR). A directly standardized relative risk (DSRR) was calculated to enable comparisons between cohorts. To compare VA enrollee mortality on military specific characteristics, we used a DOD population standard.

RESULTS

The overall VA SMR of 2.8 (95% Confidence Interval [CI] 2.8-2.9), VA utilizer SMR of 3.2 (95% CI 3.1-3.3), VA non-utilizer SMR of 0.9 (95% CI 0.8-1.1), and DOD SMR of 1.5 (95% CI 1.4-1.5) provide no evidence of a HSE in any cohort relative to the US standard population. Relative to DOD, both the total VA population SMR of 2.1 (95% CI 2.0-2.2) and the SMR for VA utilizers of 2.3 (95% CI 2.3-2.4) indicate mortality twice what would be expected given DOD mortality rates. In contrast, the VA enrollees who had not used clinical services had 40% lower than expected mortality relative to DOD.

CONCLUSIONS

No support was found for the HSE among US veterans of OEF/OIF/OND. These findings may be attributable to a number of factors including post-deployment risk-taking behavior, an abbreviated follow up period, and the nature of the OEF/OIF/OND conflict.

摘要

背景

本研究探讨了健康士兵效应(HSE)——在伊拉克和阿富汗(OEF/OIF/OND)行动中支持部署的美国(US)退伍军人的死亡率相对一般人群较低。虽然 HSE 在其他 OEF/OIF/OND 人群中得到了证实,但 OEF/OIF/OND 的美国退伍军人尚未得到系统研究。

方法

我们使用美国退伍军人事务部(VA)的行政数据,确定了以下退伍军人:(1)在 2002 年至 2011 年期间曾被部署支持 OEF/OIF/OND;(2)在 VA 医疗保健系统中登记。我们将 VA 人群分为 VA 医疗保健使用者和非使用者。我们从分析中获得了关于 OEF/OIF/OND 人群的国防部(DOD)行政数据,并获得了 VA 和 DOD 的死亡率数据,不包括战斗死亡。间接标准化用于使用风险人群总数来比较 VA 和 DOD 队列与美国人群,以计算标准化死亡率比(SMR)。计算了直接标准化相对风险(DSRR),以在队列之间进行比较。为了比较 VA 登记人员在特定军事特征方面的死亡率,我们使用了 DOD 人群标准。

结果

VA 的总体 SMR 为 2.8(95%置信区间[CI] 2.8-2.9),VA 使用者的 SMR 为 3.2(95%CI 3.1-3.3),VA 非使用者的 SMR 为 0.9(95%CI 0.8-1.1),DOD 的 SMR 为 1.5(95%CI 1.4-1.5),这表明在任何队列中都没有证据表明与美国标准人群相比存在 HSE。与 DOD 相比,VA 总人群的 SMR 为 2.1(95%CI 2.0-2.2),VA 使用者的 SMR 为 2.3(95%CI 2.3-2.4),表明死亡率是根据 DOD 死亡率预期的两倍。相比之下,与 DOD 相比,未使用临床服务的 VA 登记人员的死亡率低 40%。

结论

在 OEF/OIF/OND 的美国退伍军人中,没有发现支持 HSE 的证据。这些发现可能归因于许多因素,包括部署后的冒险行为、缩短的随访期以及 OEF/OIF/OND 冲突的性质。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5097/4367975/78af03a65744/12963_2015_40_Fig1_HTML.jpg

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