Chen Adam, Kim Jennifer, Henderson Galen, Berkowitz Aaron
Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
J Clin Neurosci. 2015 May;22(5):914-6. doi: 10.1016/j.jocn.2014.11.004. Epub 2015 Mar 20.
Autonomic dysfunction is a well-known complication of Guillain-Barré syndrome (GBS) and may manifest as hemodynamic fluctuations. Posterior reversible encephalopathy syndrome (PRES) is commonly associated with acute hypertension, but is rarely reported to occur in association with GBS. We describe a patient with GBS who developed PRES in the setting of autonomic dysfunction and review the clinical features of all 12 previously reported patients with co-occurrence of GBS and PRES. Almost all cases have occurred in women over the age of 55, raising the possibility of increased sensitivity to dysautonomia in this patient group.
自主神经功能障碍是吉兰-巴雷综合征(GBS)的一种常见并发症,可能表现为血流动力学波动。后部可逆性脑病综合征(PRES)通常与急性高血压相关,但很少报道与GBS同时发生。我们描述了一名患有GBS的患者,该患者在自主神经功能障碍的情况下发生了PRES,并回顾了之前报道的所有12例GBS和PRES同时发生患者的临床特征。几乎所有病例都发生在55岁以上的女性中,这增加了该患者群体对自主神经功能障碍敏感性增加的可能性。