Ulutaş Firdevs, Çobankara Veli, Karasu Uğur, Baser Nuri, Akbudak Ismail Hakkı
Department of Rheumatology.
Department of Internal Medicine.
Mediterr J Rheumatol. 2020 Sep 30;31(3):358-361. doi: 10.31138/mjr.31.3.358. eCollection 2020 Sep.
Systemic lupus erythematosus (SLE) is an immune-mediated, lifelong disease characterized by quite heterogeneous neuropsychiatric manifestations. Herewith, we report the first rare co-incidental case with posterior reversible encephalopathy syndrome (PRES), Guillain Barre Syndrome (GBS), and (SLE). The coexistence of these neurological conditions in SLE patients could lead to delayed diagnosis and treatment due to this rare coalescence and clinical diversity. Currently, there are no specific, diagnostic radiological or laboratory biomarkers for neurological involvement in SLE. Awareness and, early recognition of neuropsychiatric involvements of the disease are important for timely appropriate treatment. Delayed treatment may cause permanent damage, poor prognosis, long term morbidity, and even death.
系统性红斑狼疮（SLE）是一种免疫介导的终身疾病，其特征是神经精神表现非常异质性。在此，我们报告首例罕见的同时合并后部可逆性脑病综合征（PRES）、吉兰-巴雷综合征（GBS）和系统性红斑狼疮（SLE）的病例。由于这种罕见的合并情况和临床多样性，SLE患者中这些神经系统疾病的共存可能导致诊断和治疗延迟。目前，对于SLE患者神经系统受累尚无特异性的诊断性放射学或实验室生物标志物。认识并早期识别该疾病的神经精神受累情况对于及时进行适当治疗很重要。治疗延迟可能导致永久性损伤、预后不良、长期发病，甚至死亡。
