Shor Dana Ben-Ami, Barzel Joseph, Tauber Ernest, Amital Howard
Department of Medicine 'B', Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel.
Eur J Pediatr. 2015 Sep;174(9):1169-74. doi: 10.1007/s00431-015-2517-5. Epub 2015 Mar 24.
Vitamin D facilitates calcium absorption and bone building. Presence of vitamin D is highly important in pregnant women due to its effect on the development of the fetal skeleton. The study population comprised 208 low-risk pregnant women of a heterogeneous population. Maternal and fetal serum concentrations of vitamin D were measured using the Liaison 25(OH)D Assay (DiaSorin, Italy).
Maternal vitamin D serum concentrations correlate with neonatal vitamin D serum concentrations but do not affect neonatal weight and/or head circumference. WHAT IS KNOWN? • Vitamin D is known to be also involved in immunomodulation and cellular proliferation and differentiation. • Vitamin D is highly important in pregnant women for its effect on fetal musculoskeletal and neurological development. WHAT IS NEW? • No association was detected between maternal or neonatal vitamin D concentration with neonatal growth parameters or obstetrical complications, and no association was found between maternal vitamin D serum concentrations and maternal obstetrical complication rate. • A strong correlation was demonstrated between maternal and neonatal serum vitamin D concentrations.
维生素D有助于钙的吸收和骨骼生成。由于其对胎儿骨骼发育的影响,维生素D在孕妇体内的存在至关重要。研究人群包括208名来自异质人群的低风险孕妇。使用Liaison 25(OH)D检测法(DiaSorin,意大利)测量孕妇和胎儿血清中的维生素D浓度。
孕妇血清维生素D浓度与新生儿血清维生素D浓度相关,但不影响新生儿体重和/或头围。已知信息:• 已知维生素D还参与免疫调节以及细胞增殖和分化。• 维生素D对孕妇非常重要,因为它对胎儿肌肉骨骼和神经发育有影响。新发现:• 未检测到孕妇或新生儿维生素D浓度与新生儿生长参数或产科并发症之间存在关联,且未发现孕妇血清维生素D浓度与孕产妇产科并发症发生率之间存在关联。• 孕妇和新生儿血清维生素D浓度之间存在强相关性。