人附睾蛋白4在肺癌中的研究进展
[Advances of human epididymis protein 4 in lung cancer].
作者信息
Ma Qing, Wang Qian, Zhong Diansheng
机构信息
Department of Medical Oncology, The General Hospital of Tianjin Medical University, Tianjin 300052, China.
出版信息
Zhongguo Fei Ai Za Zhi. 2015 Mar;18(3):184-6. doi: 10.3779/j.issn.1009-3419.2015.03.10.
Abstract
Human epididymis 4 (HE4) belongs to whey acidic 4-disulfide center protein family. It has the characteristics of inhibiting trypsin and high expression in the serum or malignant pleural effusion of patients with lung cancer. Clinical data showed that it has certain relevance to the diagnosis and prognosis of lung cancer. HE4 may be a new indicator of clinical diagnosis and prognosis evaluation.
摘要
人附睾蛋白4（HE4）属于乳清酸性4-二硫键中心蛋白家族。它具有抑制胰蛋白酶的特性，且在肺癌患者的血清或恶性胸腔积液中高表达。临床资料表明，它与肺癌的诊断及预后具有一定相关性。HE4可能是临床诊断及预后评估的一项新指标。
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