Khan Naveed A, Siddiqui Ruqaiyyah
Pathog Glob Health. 2015 Jun;109(4):193-5. doi: 10.1179/2047773215Y.0000000009. Epub 2015 Mar 23.
Evolution of independently breeding species into males and females (gametes) has remained a puzzle. Given the significant advantages of sexual reproduction over asexual reproduction as a long-term species survival strategy; here, we pose the question whether there is some form of meiosis in Acanthamoeba species, which represents our ancient lineage. The recently available Acanthamoeba genome revealed several genes implicated in meiosis in sexual eukaryotes such as Spo11, Mre11, Rad50, Rad51, Rad52, Mnd1, Dmc1, Msh, and Mlh, suggesting that Acanthamoeba is capable of some form of meiosis, inferring the presence of sexual reproduction in Acanthamoeba, and that meiosis evolved early in eukaryotic evolution.
独立繁殖的物种进化为雄性和雌性(配子)一直是个谜。鉴于有性生殖作为一种长期的物种生存策略相对于无性生殖具有显著优势;在此,我们提出一个问题,即在代表我们古老谱系的棘阿米巴中是否存在某种形式的减数分裂。最近可得的棘阿米巴基因组揭示了几个与有性真核生物减数分裂相关的基因,如Spo11、Mre11、Rad50、Rad51、Rad52、Mnd1、Dmc1、Msh和Mlh,这表明棘阿米巴能够进行某种形式的减数分裂,由此推断棘阿米巴中存在有性生殖,并且减数分裂在真核生物进化早期就已出现。