Caprioli Richard M
Mass Spectrometry Research Center and Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA,
J Am Soc Mass Spectrom. 2015 Jun;26(6):850-2. doi: 10.1007/s13361-015-1108-z. Epub 2015 Mar 24.
Imaging mass spectrometry (IMS) has become a valuable tool for the production of molecular maps in samples ranging from solid inorganic materials to biologicals such as cells and tissues. The unique features of IMS are its ability to map a wide variety of different types of molecules, its superb molecular specificity, and its potential for discovery since no target-specific reagents are needed. IMS has made significant contributions in biology and medicine and promises to be a next generation tool in anatomic pathology.
成像质谱（IMS）已成为一种有价值的工具，可用于绘制从固体无机材料到细胞和组织等生物样本中的分子图谱。IMS的独特之处在于它能够绘制多种不同类型的分子图谱，具有卓越的分子特异性，并且由于不需要靶向特异性试剂而具有发现潜力。IMS在生物学和医学领域做出了重大贡献，并有望成为解剖病理学中的下一代工具。
