Parks Ruth Mary, Cheung Kwok-Leung
School of Medicine, University of Nottingham, Nottingham, UK.
Future Oncol. 2015;11(7):1059-70. doi: 10.2217/fon.15.21.
Improved survival from breast cancer can be attributed to a number of advances in the patient pathway from screening to advanced disease. The benefit of population screening has been established with national programs implemented. There has been improvement in the methodology of diagnostic assessment, relating to imaging techniques, methods of obtaining histological evidence and evaluation of lymph node status. Sentinel node biopsy is now routine, as is oncoplastic surgery. New forms and improved adjuvant systemic therapies are being explored. The prognosis of breast cancer can be more reliably evaluated to provide individualized information and to personalize treatments. Developments have also been seen in other areas improving the treatment and care of patients with advanced disease.
乳腺癌患者生存率的提高可归因于从筛查到晚期疾病患者治疗路径上的多项进展。随着国家筛查项目的实施，人群筛查的益处已得到证实。在诊断评估方法方面，与成像技术、获取组织学证据的方法以及淋巴结状态评估相关的方面都有了改进。前哨淋巴结活检现已成为常规操作，整形保乳手术亦是如此。新的辅助全身治疗形式和改良的辅助全身治疗正在探索之中。乳腺癌的预后能够得到更可靠的评估，从而提供个性化信息并实现治疗个体化。在改善晚期疾病患者的治疗和护理的其他领域也有进展。
