Samy Mamdouh Nabil, Khalil Hany Ezzat, Sugimoto Sachiko, Matsunami Katsuyoshi, Otsuka Hideaki, Kamel Mohamed Salah
Department of Pharmacognosy, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.
Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.
Phytochemistry. 2015 Jul;115:261-8. doi: 10.1016/j.phytochem.2015.02.020. Epub 2015 Mar 21.
Four new triterpenoids; One oleanane-, one ursane- and two cycloartane-type triterpenoids, named amphipaniculosides A-D, in addition to one new aliphatic alcohol glycoside, named amphipaniculoside E, were isolated from the 1-BuOH fraction of the leaves of Amphilophium paniculatum (L.) Kunth., together with five known compounds, (+)-lyoniresinol 3α-O-β-D-glucopyranoside, (-)-lyoniresinol 3α-O-β-D-glucopyranoside, acteoside (verbascoside), isoacteoside (isoverbascoside), and luteolin 7-O-β-D-glucopyranoside. Their structures were elucidated by spectroscopic methods including 1D and 2D NMR experiments ((1)H, (13)C, DEPT, COSY, ROESY, HSQC, HMBC) in combination with HR-ESI-MS and by comparisons of their physical and spectroscopic data with literature values.
从圆锥花大萼距花（Amphilophium paniculatum (L.) Kunth.）叶片的正丁醇萃取物中，分离得到了四种新的三萜类化合物，即一个齐墩果烷型、一个乌苏烷型和两个环阿尔廷烷型三萜类化合物，命名为双圆锥花苷A - D，此外还得到了一种新的脂肪醇糖苷，命名为双圆锥花苷E，同时还分离出了五种已知化合物，分别为(+)-裂环马钱子苷3α - O - β - D - 吡喃葡萄糖苷、(-)-裂环马钱子苷3α - O - β - D - 吡喃葡萄糖苷、洋地黄苷（毛蕊花糖苷）、异洋地黄苷（异毛蕊花糖苷）和木犀草素7 - O - β - D - 吡喃葡萄糖苷。通过包括一维和二维核磁共振实验（(1)H、(13)C、DEPT、COSY、ROESY、HSQC、HMBC）在内的光谱方法，结合高分辨电喷雾电离质谱，并将其物理和光谱数据与文献值进行比较，确定了它们的结构。
