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神经外科和神经重症患者血栓预防及抗凝或抗血小板治疗的全国性调查。

National survey on thromboprophylaxis and anticoagulant or antiplatelet management in neurosurgical and neurocritical patients.

作者信息

Vázquez-Alonso E, Fábregas N, Rama-Maceiras P, Ingelmo Ingelmo I, Valero Castell R, Valencia Sola L, Iturri Clavero F

机构信息

Servicio de Anestesiología, Hospital Universitario Virgen de las Nieves, Granada, España.

Servicio de Anestesiología, Hospital Clínic, Universitat de Barcelona, Barcelona, España.

出版信息

Rev Esp Anestesiol Reanim. 2015 Dec;62(10):557-64. doi: 10.1016/j.redar.2015.01.016. Epub 2015 Mar 21.

Abstract

OBJECTIVES

To determine the protocols used by Spanish anaesthesiologists for thromboprophylaxis and anticoagulant or antiplatelet drugs management in neurosurgical or neurocritical care patients.

MATERIAL AND METHODS

An online survey with 22 questions, with one or multiple options, launched by the Neuroscience Subcommittee of the Spanish Anaesthesia Society and available between June and October 2012.

RESULTS

Of the 73 hospitals included in the National Hospitals Catalogue, a valid response to the online questionnaire was received by 41 anaesthesiologists from 37 sites (response rate 50.7%). Only one response per site was used. A specific protocol was available in 27% of these centres. Mechanical thromboprophylaxis is used, intraoperatively or postoperatively, in 80%, and pharmacological treatment is used by 75% of respondents. Enoxaparin was the most frequent heparin used in craniotomy patients (78%). Craniotomies were performed maintaining acetylsalicylic acid treatment in patients with coronary stents and double anti-platelet treatment in a half of the centres.

CONCLUSIONS

Mechanical thromboprophylaxis is used more frequently than the pharmacological approach in neurosurgical or neurocritical populations in Spanish hospitals. Management of patients under previous anticoagulant treatment was highly heterogeneous among hospitals included in this survey. Previous antiplatelet treatment is modified depending on primary or secondary prescription.

摘要

目的

确定西班牙麻醉医生在神经外科或神经重症监护患者中进行血栓预防以及管理抗凝或抗血小板药物所采用的方案。

材料与方法

由西班牙麻醉学会神经科学小组委员会发起一项包含22个问题的在线调查,问题有单项或多项选择,于2012年6月至10月期间开放作答。

结果

在国家医院目录中的73家医院里,来自37个机构的41名麻醉医生对在线问卷给出了有效回复(回复率50.7%)。每个机构仅采用一份回复。这些中心中有27%有特定方案。80%的受访者在术中或术后采用机械性血栓预防措施,75%采用药物治疗。依诺肝素是开颅手术患者中最常用的肝素(78%)。在有冠状动脉支架的患者进行开颅手术时,部分中心维持阿司匹林治疗,另一半中心采用双重抗血小板治疗。

结论

在西班牙医院的神经外科或神经重症患者中,机械性血栓预防措施的使用比药物治疗更为频繁。在本次调查涵盖的医院中,先前接受抗凝治疗患者的管理存在高度异质性。先前的抗血小板治疗会根据一级或二级处方进行调整。

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