Dettori-Gera C, Ronner P, Scarpa A
Biochim Biophys Acta. 1985 May 8;839(3):281-6. doi: 10.1016/0304-4165(85)90010-8.
We studied the glucose dependence of insulin and somatostatin release from rat pancreata, which were perfused in vitro in the presence of 3-isobutyl-1-methylxanthine (IBMX; 0.5 mM). Half-maximal insulin release occurred at approx. 12 mM glucose, and half-maximal somatostatin release at approx. 7 mM glucose.
我们研究了大鼠胰腺中胰岛素和生长抑素释放对葡萄糖的依赖性，这些胰腺在3-异丁基-1-甲基黄嘌呤（IBMX；0.5 mM）存在的情况下进行体外灌注。胰岛素释放达到半最大量时的葡萄糖浓度约为12 mM，生长抑素释放达到半最大量时的葡萄糖浓度约为7 mM。
