Targeting MET and EGFR in NSCLC-what can we learn from the recently reported phase III trial of onartuzumab in combination with erlotinib in advanced non-small cell lung cancer?
作者信息
Charakidis Michail, Boyer Michael
机构信息
Chris O'Brien Lifehouse, Department of Medical Oncology, Camperdown, NSW 2050, Australia.
出版信息
Transl Lung Cancer Res. 2014 Dec;3(6):395-6. doi: 10.3978/j.issn.2218-6751.2014.09.03.
Abstract
摘要
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Targeting MET and EGFR in NSCLC-what can we learn from the recently reported phase III trial of onartuzumab in combination with erlotinib in advanced non-small cell lung cancer?在非小细胞肺癌中靶向MET和EGFR——我们能从最近报道的奥那珠单抗联合厄洛替尼治疗晚期非小细胞肺癌的III期试验中学到什么？
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本文引用的文献
1
Results From the Phase III Randomized Trial of Onartuzumab Plus Erlotinib Versus Erlotinib in Previously Treated Stage IIIB or IV Non-Small-Cell Lung Cancer: METLung.METLung：奥沙利umab 联合厄洛替尼对比厄洛替尼治疗既往治疗的 IIIB 或 IV 期非小细胞肺癌的 III 期随机试验结果
J Clin Oncol. 2017 Feb;35(4):412-420. doi: 10.1200/JCO.2016.69.2160. Epub 2016 Dec 12.
2
Targeting MET Amplification as a New Oncogenic Driver.针对 MET 扩增作为一种新的致癌驱动因素。
Cancers (Basel). 2014 Jul 22;6(3):1540-52. doi: 10.3390/cancers6031540.
3
Randomized phase II trial of Onartuzumab in combination with erlotinib in patients with advanced non-small-cell lung cancer.随机 II 期试验：奥沙利umab 联合厄洛替尼治疗晚期非小细胞肺癌患者。
J Clin Oncol. 2013 Nov 10;31(32):4105-14. doi: 10.1200/JCO.2012.47.4189. Epub 2013 Oct 7.
4
Erlotinib in previously treated non-small-cell lung cancer.厄洛替尼用于既往接受过治疗的非小细胞肺癌。
N Engl J Med. 2005 Jul 14;353(2):123-32. doi: 10.1056/NEJMoa050753.
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