Department of Internal Medicine, Ataturk University, Erzurum, Turkey.
Eur Rev Med Pharmacol Sci. 2015;19(5):767-71.
Interatrial block (IAB) connotes a P wave duration ≥ 110 msec on electrocardiography (ECG). P-terminal force corresponds to a biphasic P wave with its terminal negative phase ≥ 40 msec x mm in V1 derivation on ECG. IAB and P-terminal force are closely related parameters and they are accepted as predictors for left atrial dysfunction, left atrial dilatation, atrial fibrillation and strokes. Left atrial functions in chronic haemodialysis patients becomes worse in the course of time because of long standing pressure and volume overload. The aim of this study is to evaluate the relationship between IAB, P-terminal force and left atrial functions.
68 chronic haemodialysis patients and 60 control subjects were included in the study. Conventional echocardiography and left atrial dynamic functions were measured in all cases. The subjects with IAB and P-terminal force on ECG were identified.
Left ventricular size, wall thickness and left atrial diameters were significantly greater in haemodialysis patients than the control group (p < 0.001). 42 (62%) patients had IAB (≥ 110 msec) and 45 (66%) patients had P-terminal force ( ≥ 40 msec x mm) in the haemodialysis group. Left atrial reservoir, conduit and pump functions were significantly lower in the haemodialysis group than the control group (p < 0.001). There was a statistically significant correlation between left atrial functions, IAB (≥ 110 msec) and P-terminal force (≥ 40msec x mm) in all parameters (p < 0.001).
This study showed that decreased left atrial functions in chronic haemodialysis patients are closely correlated with IAB and P-terminal force.
心电图（ECG）上的房内传导阻滞（IAB）表示 P 波持续时间≥110ms。P 波终末电势对应于心电图 V1 导联上双相 P 波，其终末负相≥40ms×mm。IAB 和 P 波终末电势是密切相关的参数，它们被认为是左心房功能障碍、左心房扩张、心房颤动和中风的预测指标。由于长期的压力和容量超负荷，慢性血液透析患者的左心房功能随着时间的推移而恶化。本研究旨在评估 IAB、P 波终末电势与左心房功能之间的关系。
纳入 68 例慢性血液透析患者和 60 例对照组。所有患者均行常规超声心动图和左心房动态功能检查。确定心电图上有 IAB 和 P 波终末电势的患者。
与对照组相比，血液透析患者的左心室大小、壁厚度和左心房直径明显增大（p<0.001）。42（62%）例血液透析患者存在 IAB（≥110ms），45（66%）例患者存在 P 波终末电势（≥40ms×mm）。与对照组相比，血液透析组的左心房储备、传导和泵功能明显降低（p<0.001）。所有参数中，左心房功能、IAB（≥110ms）和 P 波终末电势（≥40ms×mm）之间均存在统计学显著相关性（p<0.001）。
本研究表明，慢性血液透析患者左心房功能下降与 IAB 和 P 波终末电势密切相关。
