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上颌窦后鼻孔息肉的临床表现及病理特征的患病率

The prevalence of clinical presentations and pathological characteristics of antrochoanal polyp.

作者信息

Sarafraz Mozafar, Niazi Amir, Araghi Somayeh

出版信息

Niger J Med. 2015 Jan-Mar;24(1):12-6.

PMID:25807668
Abstract

OBJECTIVE

Antrochoanal polyps (ACPs) originating from the maxillary sinus, are considered as benign inflammatory lesions. In fact, these polyps are the hypertrophy of the mucous membrane of the maxillary sinus, which for unknown reasons grow through the maxillary sinus ostium towards the other portions of the nasal cavity and the choana, such a way that they may grow all the way to the nasopharynx and even oropharynx. ACP is usually unilateral however, the bilateral forms have been observed in some instances. Its most frequent clinical manifestations are nasal obstruction and rhinorrhea, whereas in many cases some other presentations such as epistaxis, dyspnea, and dysphagia, and weight loss have been also noticed. The aim of this study was to investigate the relative prevalence of clinical manifestations and pathological characteristics in 87 patients with ACPs during a period of 15 years in this hospital.

METHODS

It was a descriptive cross-sectional study, accomplished retrospectively, and based on existing data in the records of the patients admitted in Imam Khomeini Hospital of Ahvaz. In this study, the patients above 16 years old have been considered as adults. Each patient's data were collected using a questionnaire. Data analysis was performed by the statistical SPSS software (descriptive statistics and Chi-square test).

RESULTS

87 patients were registered with the diagnosis of ACP during 1999 and 2014. Out of these patients 60% were females and 40% were males. Predominant clinical manifestation was nasal obstruction with an incidence of 39%; and the least frequent manifestation was weight loss with an incidence of 0%. Moreover, the left nasal cavity was more involved with the incidence of 55%. Among the existing surgical techniques. Functional Endoscopic Sinus Surgery (FESS), Caldwell- Luc procedure, and combined approach were the most common applied techniques,with frequencies of 64%, 24% and 12%, respectively. Confidence Interval (CI) = 0.03 ± 0.2, Odd ratio = 0.26, and p = 0.21.

CONCLUSION

Nasal obstruction was the predominant clinical symptom of ACP. The left nasal cavity was more involved than the right-side. FESS was the commonest employed surgical procedure; and the inflammatory pattern has been the most pathological presentation.

摘要

目的

起源于上颌窦的鼻后孔息肉(ACPs)被认为是良性炎性病变。实际上,这些息肉是上颌窦黏膜的肥大,其因不明原因通过上颌窦口向鼻腔和鼻后孔的其他部分生长,以至于它们可能一直生长到鼻咽部甚至口咽部。ACPs通常为单侧性,不过,在某些情况下也观察到双侧形式。其最常见的临床表现是鼻塞和流涕,而在许多病例中还注意到一些其他表现,如鼻出血、呼吸困难、吞咽困难和体重减轻。本研究的目的是调查该医院15年间87例ACPs患者临床表现和病理特征的相对患病率。

方法

这是一项描述性横断面研究,采用回顾性研究方法,基于阿瓦士伊玛目霍梅尼医院收治患者记录中的现有数据。在本研究中,16岁以上患者被视为成年人。使用问卷收集每位患者的数据。数据分析通过统计软件SPSS进行(描述性统计和卡方检验)。

结果

1999年至2014年期间登记诊断为ACPs的患者有87例。其中60%为女性,40%为男性。主要临床表现为鼻塞,发生率为39%;最不常见的表现是体重减轻,发生率为0%。此外,左侧鼻腔受累更多,发生率为55%。在现有的手术技术中,功能性鼻内镜鼻窦手术(FESS)、柯德威尔 - 卢氏手术和联合手术是最常用的技术,频率分别为64%、24%和12%。置信区间(CI)= 0.03 ± 0.2,比值比 = 0.26,p = 0.21。

结论

鼻塞是ACPs的主要临床症状。左侧鼻腔比右侧受累更多。FESS是最常用的外科手术;炎性模式是最主要的病理表现。

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The prevalence of clinical presentations and pathological characteristics of antrochoanal polyp.上颌窦后鼻孔息肉的临床表现及病理特征的患病率
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