Mandong Barnabas M, Emmanuel Innocent, Vandi Kwaghe B, Shilong Danaan, Karshima Jonathan A, Olowu Babatunde A
Niger J Med. 2015 Jan-Mar;24(1):81-3.
Choriocarcinoma metastasizes widely. One in every ten choriocarcinoma that leaves its primary site, metastasizes to the brain. This 27 years old patient presented with symptoms of space occupying lesion that was confirmed by CT-SCAN. There was no history of vaginal bleeding and amenorrhoea was concealed by unmarried patient. Chest X-ray was normal. Tumor was excised after craniotomy. Histology of tumor was that of secondary choriocarcinoma. Patient responded excellently to chemotherapy and was well one year after. We strongly recommend a high index of suspicion of choriocarcinoma in management of brain tumors. β-HCG assay should be included in investigation of all patients with intracranial tumors irrespective of sex.
绒毛膜癌转移广泛。每十例离开原发部位的绒毛膜癌中，就有一例转移至脑部。这位27岁的患者表现出占位性病变的症状，CT扫描证实了这一点。患者无阴道出血史，未婚患者隐瞒了闭经情况。胸部X光检查正常。开颅术后切除了肿瘤。肿瘤组织学检查为继发性绒毛膜癌。患者对化疗反应良好，一年后情况良好。我们强烈建议在脑肿瘤的管理中高度怀疑绒毛膜癌。无论性别，所有颅内肿瘤患者的检查都应包括β-HCG检测。
