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[古病理学中的肿瘤:来自木乃伊的证据]

[Tumors in paleopathology: evidences from mummies].

作者信息

Giuffra Valentina, Fornaciari Gino

机构信息

Dipartimento di Oncologia, dei Trapianti e delle Nuove Tecnologie in Medicina, Divisione di Paleopatologia, Storia della Medicina e Bioetica, Università di Pisa, Pisa, I.

出版信息

Med Secoli. 2013;25(1):35-50.

Abstract

The relative abundance of neoplastic lesions documented so far in paleopathological literature, distributed over a wide lapse of time and in different geographic areas, demonstrates that a number of tumours affected past populations. Nevertheless, if dozens of cases of tumors affecting the skeleton are reported, only afew records are documented in soft tissues. The rarity of tumors in mummies is a debated problem; short life span of past populations, scarcity of mummified remains arrived to us in comparison with skeletal remains and technical difficulties to detect neoplastic lesions in ancient tissues seem to be the main reasons of the rarity of findings. It is important to pay maximum attention to any little sign of neoplastic lesion in ancient human remains, in order to increase our limited knowledge about the type of tumours and relative incidence afflicting our ancestors. Comparison with modern data could help understand the evolution patterns of cancer in the history of Mankind.

摘要

迄今为止,古病理学文献中记录的肿瘤性病变的相对丰度,分布在很长一段时间内且在不同地理区域,表明过去的人群受到多种肿瘤的影响。然而,如果报告了数十例影响骨骼的肿瘤病例,那么软组织中的记录却很少。木乃伊中肿瘤的罕见性是一个有争议的问题;过去人群的寿命较短、与骨骼遗骸相比我们获得的木乃伊遗骸稀少,以及在古代组织中检测肿瘤性病变的技术困难,似乎是发现稀少的主要原因。重要的是要极其关注古代人类遗骸中肿瘤性病变的任何微小迹象,以增加我们对折磨我们祖先的肿瘤类型和相对发病率的有限认识。与现代数据进行比较有助于了解人类历史上癌症的演变模式。

相似文献

2
Soft tissue tumors in palaeopathology: a review.古病理学中的软组织肿瘤:综述。
Pathobiology. 2012;79(5):257-67. doi: 10.1159/000337292. Epub 2012 Jun 21.
3
Histology of ancient soft tissue tumors: A review.古代软组织肿瘤的组织学:综述
Int J Paleopathol. 2018 Jun;21:64-76. doi: 10.1016/j.ijpp.2017.02.007. Epub 2017 Mar 21.

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