El Habr Constantin, Meguerian Zarouwi, Sammour Rita
J Med Liban. 2014 Oct-Nov;62(4):238-40. doi: 10.12816/0008295.
Tumor necrosis factor (TNF)-α inhibitors are being widely and increasingly used for the management of a spectrum of rheumatologic diseases that are refractory to conventional disease modifying anti-rheumatic drugs. Various cutaneous side effects have been reported after treatment with TNF-α inhibitors. We present a case report of a 26-year-old male patient who developed a lichenoid drug eruption few months after the initiation of adalimumab for the management of Crohn's disease. We also highlight the clinical and histopathologic differences between lichenoid drug eruptions and idiopathic lichen planus.
肿瘤坏死因子（TNF）-α抑制剂正被广泛且越来越多地用于治疗一系列对传统抗风湿药物难治的风湿性疾病。使用TNF-α抑制剂治疗后已报告了各种皮肤副作用。我们报告一例26岁男性患者的病例，该患者在开始使用阿达木单抗治疗克罗恩病几个月后出现苔藓样药疹。我们还强调了苔藓样药疹与特发性扁平苔藓在临床和组织病理学上的差异。
