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肌肉骨骼感染治疗策略与挑战的临床视角

A clinical perspective on musculoskeletal infection treatment strategies and challenges.

作者信息

Shirwaiker Rohan A, Springer Bryan D, Spangehl Mark J, Garrigues Grant E, Lowenberg David W, Garras David N, Yoo Jung U, Pottinger Paul S

出版信息

J Am Acad Orthop Surg. 2015 Apr;23 Suppl:S44-54. doi: 10.5435/JAAOS-D-14-00379.

DOI:10.5435/JAAOS-D-14-00379
PMID:25808969
Abstract

Orthopaedic implants improve the quality of life of patients, but the risk of postoperative surgical site infection poses formidable challenges for clinicians. Future directions need to focus on prevention and treatment of infections associated with common arthroplasty procedures, such as the hip, knee, and shoulder, and nonarthroplasty procedures, including trauma, foot and ankle, and spine. Novel prevention methods, such as nanotechnology and the introduction of antibiotic-coated implants, may aid in the prevention and early treatment of periprosthetic joint infections with goals of improved eradication rates and maintaining patient mobility and satisfaction.

摘要

骨科植入物改善了患者的生活质量,但术后手术部位感染的风险给临床医生带来了巨大挑战。未来的方向需要聚焦于与常见关节置换手术(如髋、膝和肩)以及非关节置换手术(包括创伤、足踝和脊柱)相关的感染的预防和治疗。新型预防方法,如纳米技术和引入抗生素涂层植入物,可能有助于假体周围关节感染的预防和早期治疗,目标是提高根除率并维持患者的活动能力和满意度。

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