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从受影响工作场所选取的9·11世贸中心袭击事件幸存者中,灾后重度抑郁症相对于创伤后应激障碍的患病率。

The postdisaster prevalence of major depression relative to PTSD in survivors of the 9/11 attacks on the World Trade Center selected from affected workplaces.

作者信息

North Carol S, Pollio David E, Hong Barry A, Pandya Anand, Smith Rebecca P, Pfefferbaum Betty

机构信息

Program in Trauma and Disaster and Staff Psychiatrist, VA North Texas Health Care System, Dallas, TX, USA; Departments of Psychiatry and Emergency Medicine, The University of Texas Southwestern Medical Center, 6363 Forest Park Rd., Dallas, TX 75390-8828, USA.

The University of Alabama at Birmingham, Department of Social Work, College of Arts and Sciences, Birmingham, AL, USA.

出版信息

Compr Psychiatry. 2015 Jul;60:119-25. doi: 10.1016/j.comppsych.2015.02.009. Epub 2015 Feb 20.

Abstract

BACKGROUND

Studies of survivors of the September 11, 2001 attacks on the World Trade Center in New York City suggest that postdisaster depressive disorders may be at least as prevalent, or even more prevalent, than posttraumatic stress disorder (PTSD), unlike findings from most other disaster studies. The relative prevalence and incidence of major depressive disorder (MDD) and PTSD were examined after the 9/11 attacks relative to trauma exposures.

METHODS

This study used full diagnostic assessment methods and careful categorization of exposure groups based on DSM-IV-TR criteria for PTSD to examine 373 employees of 9/11-affected New York City workplaces.

RESULTS

Postdisaster new MDD episode (26%) in the entire sample was significantly more prevalent (p<.001) than 9/11-related PTSD (14%). Limiting the comparison to participants with 9/11 trauma exposures, the prevalence of postdisaster new MDD episode and 9/11-related PTSD did not differ (p=.446). The only 9/11 trauma exposure group with a significant difference in relative prevalence of MDD and PTSD were those with a 9/11 trauma-exposed close associate, for whom postdisaster new MDD episode (45%) was more prevalent (p=.046) than 9/11-related PTSD (31%).

CONCLUSIONS

Because of the conditional definition of PTSD requiring trauma exposure that is not part of MDD criteria, prevalence comparisons of these two disorders must be limited to groups with qualifying trauma exposures to be meaningful. Findings from this study suggest distinct mechanisms underlying these two disorders that differentially relate to direct exposure to trauma vs. the magnitude of the disaster and personal connectedness to disaster and community-wide effects.

摘要

背景

对2001年9月11日纽约市世贸中心袭击事件幸存者的研究表明,与大多数其他灾难研究的结果不同,灾后抑郁症的患病率可能至少与创伤后应激障碍(PTSD)一样高,甚至更高。相对于创伤暴露情况,对9·11袭击事件后重度抑郁症(MDD)和PTSD的相对患病率及发病率进行了研究。

方法

本研究采用全面的诊断评估方法,并根据PTSD的《精神疾病诊断与统计手册》第四版修订版(DSM-IV-TR)标准对暴露组进行仔细分类,以研究受9·11事件影响的纽约市工作场所的373名员工。

结果

整个样本中灾后新发MDD发作(26%)的患病率显著高于与9·11相关的PTSD(14%)(p<0.001)。将比较限于有9·11创伤暴露的参与者,灾后新发MDD发作和与9·11相关的PTSD的患病率没有差异(p = 0.446)。在MDD和PTSD相对患病率上有显著差异的唯一9·11创伤暴露组是那些有9·11创伤暴露的亲密同伴的人,他们灾后新发MDD发作(45%)的患病率高于与9·11相关的PTSD(31%)(p = 0.046)。

结论

由于PTSD的条件性定义要求创伤暴露不属于MDD标准的一部分,这两种疾病的患病率比较必须限于有符合条件的创伤暴露的组才有意义。本研究结果表明这两种疾病有不同的潜在机制,分别与直接暴露于创伤、灾难的严重程度以及个人与灾难和社区范围影响的关联程度有关。

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