2013 - 14年流感季节美国佛罗里达州甲型H1N1流感疾病的严重程度及D225G变异株的出现
Severity of influenza A(H1N1) illness and emergence of D225G variant, 2013-14 influenza season, Florida, USA.
作者信息
Iovine Nicole M, Morris J Glenn, Fredenburg Kristianna, Rand Kenneth, Alnuaimat Hassan, Lipori Gloria, Brew Joseph, Lednicky John A
出版信息
Emerg Infect Dis. 2015 Apr;21(4):664-7. doi: 10.3201/eid2104.141375.
Abstract
Despite a regional decline in influenza A(H1N1)pdm09 virus infections during 2013-14, cases at a Florida hospital were more severe than those during 2009-10. Examined strains had a hemagglutinin polymorphism associated with enhanced binding to lower respiratory tract receptors. Genetic changes in this virus must be monitored to predict the effect of future pandemic viruses.
摘要
尽管2013 - 14年甲型H1N1流感大流行病毒（A(H1N1)pdm09）感染在该地区有所下降，但佛罗里达州一家医院的病例比2009 - 10年更为严重。所检测的毒株具有一种与增强对下呼吸道受体结合相关的血凝素多态性。必须监测该病毒的基因变化，以预测未来大流行病毒的影响。
Zotero 插件