Zaidi Ali Ashher, Van Brunt Bruce, Wake Graeme Charles
Institute of Natural and Mathematical Sciences, Massey University, Auckland, New Zealand.
Math Biosci Eng. 2015 Jun;12(3):491-501. doi: 10.3934/mbe.2015.12.491.
We present a model that describes the growth, division and death of a cell population structured by size. The model is an extension of that studied by Hall and Wake (1989) and incorporates the asymmetric division of cells. We consider the case of binary asymmetrical splitting in which a cell of size ε divides into two daughter cells of different sizes and find the steady size distribution (SSD) solution to the non-local differential equation. We then discuss the shape of the SSD solution. The existence of higher eigenfunctions is also discussed.
我们提出了一个描述按大小结构的细胞群体生长、分裂和死亡的模型。该模型是霍尔和韦克(1989年)所研究模型的扩展,并纳入了细胞的不对称分裂。我们考虑二元不对称分裂的情况,即大小为ε的细胞分裂成两个大小不同的子细胞,并找到了非局部微分方程的稳态大小分布(SSD)解。然后我们讨论了SSD解的形状。还讨论了高阶本征函数的存在性。