Odoevskaia I M
Med Parazitol (Mosk). 2014 Oct-Dec(4):28-31.
Whether experimentally infected female rats can transmit Trichinella in utero and its invasion may affect the immunity of their offspring has been investigated. There is evidence that maternal antibodies have a significant impact on the humoral immunity of the offspring and as a result on the number of Trichinella larvae accustomed in the muscles. Immune interlayer formation in the populations of carnivorous mammals in the endemic areas occurs due to reinvasions and passive transmission of maternal antibodies to the offspring. High-tension immunity in the population and animals contributes to a reduction in the onset of invasion and to a predominance of the subclinical course of the disease and asymptomatic carriage in a specific focus. Passive immunity transmitted from the Trichinella-infected mother to its offspring is of importance in the development of epidemic and epizootic processes in the natural and synanthropic foci of trichinosis.
已对实验感染的雌性大鼠是否能在子宫内传播旋毛虫及其感染是否会影响其后代的免疫力进行了研究。有证据表明,母源抗体对后代的体液免疫有重大影响,进而影响肌肉中旋毛虫幼虫的数量。在流行地区,食肉哺乳动物群体中免疫夹层的形成是由于再次感染以及母源抗体向后代的被动传递。群体和动物中的高张力免疫有助于减少感染的发生,并导致疾病在特定疫源地以亚临床病程为主且无症状携带。从感染旋毛虫的母亲传递给其后代的被动免疫在旋毛虫病自然疫源地和共生疫源地的流行和 epizootic 过程发展中具有重要意义。 (注:“epizootic”这个词在兽医领域常指动物流行病,这里结合语境可能是想说动物疫病流行相关过程,但不确定是特定专业含义,如果是准确翻译需要根据更多专业背景知识,目前暂按原样翻译。)