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[源自胃癌并伴有癌相关性弥散性血管内凝血的骨髓弥漫性癌病经重组人可溶性血栓调节蛋白成功治疗的病例报告]

[Case report of disseminated carcinomatosis of the bone marrow originating from gastric cancer with cancer-related disseminated intravascular coagulation successfully treated with recombinant human soluble thrombomodulin].

作者信息

Kawamoto Hiroshi, Uchida Yoichiro, Ueda Shugo, Yanagita Soshi, Terajima Hiroaki

机构信息

Dept. of Gastroenterological Surgery and Oncology, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital.

出版信息

Gan To Kagaku Ryoho. 2015 Mar;42(3):363-5.

Abstract

A 62-year-old man, who underwent distal gastrectomy due to gastric cancer, was diagnosed with disseminated carcinomatosis of the bone marrow 8 years later. Chemotherapy was administered following treatment with recombinant human soluble thrombomodulin (rTM), and as a result, he successfully recovered from his disseminated intravascular coagulation (DIC) status and experienced improvement of his severe cancer-related pain. The use of rTM may enable the safe continuation of chemotherapy, and rTM may also be a useful treatment for DIC associated with solid cancer, such as gastric cancer.

摘要

一名62岁男性因胃癌接受了远端胃切除术,8年后被诊断为骨髓播散性癌病。在用重组人可溶性血栓调节蛋白(rTM)治疗后进行了化疗,结果,他成功从弥散性血管内凝血(DIC)状态中恢复,并经历了严重癌症相关疼痛的改善。rTM的使用可能使化疗得以安全持续,并且rTM也可能是治疗与实体癌(如胃癌)相关的DIC的有效方法。

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