Benitez Erik, Sumpio Brandon J, Chin Jason, Sumpio Bauer E
Department of Vascular Surgery, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510.
Department of Vascular Surgery, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510.
Semin Vasc Surg. 2014 Mar;27(1):3-15. doi: 10.1053/j.semvascsurg.2014.12.001. Epub 2014 Dec 10.
Significant progress in limb salvage for patients with peripheral arterial disease and critical limb ischemia has occurred in the past 2 decades. Improved patient outcomes have resulted from increased knowledge and understanding of the disease processes, as well as efforts to improve revascularization techniques and enhance patient care after open and endovascular procedures. An imaging modality that is noninvasive, fast, and safe would be a useful tool for clinicians in assessing lower-extremity perfusion when planning interventions. Among the current and emerging regional perfusion imaging modalities are transcutaneous oxygen monitoring, hyperspectral imaging, indocyanine green dye-based fluorescent angiography, nuclear diagnostic imaging, and laser Doppler. These tests endeavor to delineate regional foot perfusion to guide directed revascularization therapy in patients with critical limb ischemia and foot ulceration.
在过去20年里，外周动脉疾病和严重肢体缺血患者的保肢治疗取得了重大进展。对疾病过程的认识和理解不断增加，以及在开放手术和血管内手术后努力改进血管重建技术并加强患者护理，从而改善了患者的治疗效果。一种无创、快速且安全的成像方式对于临床医生在规划干预措施时评估下肢灌注情况将是一个有用的工具。当前和新兴的区域灌注成像方式包括经皮氧监测、高光谱成像、基于吲哚菁绿染料的荧光血管造影、核诊断成像和激光多普勒。这些检查致力于描绘足部区域灌注情况，以指导严重肢体缺血和足部溃疡患者的定向血管重建治疗。
