Liss L A
Tsitologiia. 1985 Mar;27(3):342-5.
Using double immunofluorescence staining, microtubules and intermediate filaments were shown to have similar distribution in the substrate-spread mouse embryo fibroblasts. However, in cells spreading on the substrate, microtubules grow from the centre to the periphery regions quicker than intermediate filaments. We suppose that microtubules may guide the spreading of intermediate filaments from the perinuclear regions to the periphery of the cell during its spreading.
使用双重免疫荧光染色法显示，在贴壁铺展的小鼠胚胎成纤维细胞中，微管和中间丝具有相似的分布。然而，在贴壁铺展的细胞中，微管从细胞中心向周边区域生长的速度比中间丝更快。我们推测，在细胞铺展过程中，微管可能引导中间丝从核周区域向细胞周边铺展。
