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肉毒梭菌A2B3 87全基因组序列，该菌株为意大利一起食源性肉毒中毒致死病例中涉及的高毒力菌株。

Whole-Genome Sequence of Clostridium botulinum A2B3 87, a Highly Virulent Strain Involved in a Fatal Case of Foodborne Botulism in Italy.

作者信息

Giordani Francesco, Fillo Silvia, Anselmo Anna, Palozzi Anna Maria, Fortunato Antonella, Gentile Bernardina, Pittiglio Valentina, Spagnolo Ferdinando, Anniballi Fabrizio, Fiore Alfonsina, Auricchio Bruna, De Medici Dario, Lista Florigio

机构信息

Histology and Molecular Biology Section Army Medical and Veterinary Research Center, Rome, Italy.

National Reference Center for Botulism, Department of Veterinary Public Health and Food Safety, Istituto Superiore di Sanità (ISS), Rome, Italy.

出版信息

Genome Announc. 2015 Mar 26;3(2):e00237-15. doi: 10.1128/genomeA.00237-15.

DOI:10.1128/genomeA.00237-15
PMID:25814616
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4384156/
Abstract

Here, we report the genome sequence of a rare bivalent strain of Clostridium botulinum, A2B3 87. The strain was isolated from a foodborne botulism case that occurred in Italy in 1995. The case was characterized by rapid evolution of the illness and failure of conventional treatments.

摘要

在此，我们报告了一种罕见的二价肉毒梭菌菌株A2B3 87的基因组序列。该菌株是从1995年发生在意大利的一起食源性肉毒中毒病例中分离出来的。该病例的特点是病情迅速发展且传统治疗方法无效。

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