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肾移植受者中的罕见真菌感染。

Unusual fungal infections in renal transplant recipients.

作者信息

Eswarappa Mahesh, Varma P Vijay, Madhyastha Rakesh, Reddy Sujeeth, Gireesh M S, Gurudev K C, Mysorekar Vijaya V, Hemanth Beena

机构信息

Department of Nephrology, M. S. Ramaiah Medical College and Teaching Hospital, MSR Nagar, MSRIT Post, Bangalore, Karnataka 560054, India.

Department of Pathology, M. S. Ramaiah Medical College and Teaching Hospital, MSR Nagar, MSRIT Post, Bangalore, Karnataka 560054, India.

出版信息

Case Rep Transplant. 2015;2015:292307. doi: 10.1155/2015/292307. Epub 2015 Feb 26.

Abstract

Fungal infections are an important cause of morbidity and mortality in renal transplant recipients. The causative agent and the risk factors differ depending on the period after the kidney transplant. Also the incidence varies according to the geographical area. We are reporting three cases of fungal infections in renal transplant recipients. Two of them have etiological agents which are common among immunosuppressed patients, but with an atypical clinical presentation, while one of them is a subcutaneous infection caused by a less frequent dematiaceous fungus, Aureobasidium pullulans. These cases highlight how a high index of clinical suspicion and prompt diagnosis is very much essential for better outcome. The emerging fungal infections and paucity of data regarding their management pose a challenge to the transplant physicians.

摘要

真菌感染是肾移植受者发病和死亡的重要原因。病原体和危险因素因肾移植后的时期而异。发病率也因地理区域而异。我们报告了3例肾移植受者的真菌感染病例。其中2例的病原体在免疫抑制患者中较为常见,但临床表现不典型,而其中1例是由一种较罕见的暗色真菌——出芽短梗霉引起的皮下感染。这些病例凸显了高度的临床怀疑和及时诊断对于取得更好治疗效果至关重要。新出现的真菌感染以及关于其治疗的数据匮乏给移植医生带来了挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60df/4357039/b2bc88090773/CRIT2015-292307.001.jpg

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