Daugherty Emily, Bhavsar Shripal, Hahn Seung Shin, Bassano Daniel, Hall Walter
Departments of 1Radiation Oncology and.
2Department of Radiation Oncology, Integris Cancer Institute, Oklahoma City, Oklahoma.
J Neurosurg. 2015 Jun;122(6):1324-9. doi: 10.3171/2014.9.JNS13959. Epub 2015 Mar 27.
Trigeminal neuralgia is a common pain syndrome primarily managed medically, although many patients require surgical or radiotherapeutic intervention. Stereotactic radiosurgery has become a preferred method of treatment given its high efficacy rates and relatively favorable toxicity profile. However, many patients have refractory pain even after repeat courses of stereotactic radiosurgery. Historically, 2 courses have been the limit in such patients. The authors present a case of multiply recurrent trigeminal neuralgia treated with a third course of radiosurgery in which the patient had successful pain control and no additional toxicity. Meticulous attention to the therapeutic technique allows the continued application of stereotactic radiosurgery in patients.
三叉神经痛是一种常见的疼痛综合征,主要通过药物治疗,不过许多患者需要手术或放射治疗干预。立体定向放射外科因其高有效率和相对良好的毒性特征,已成为一种首选的治疗方法。然而,许多患者即使在接受多次立体定向放射外科治疗后仍有顽固性疼痛。从历史上看,这类患者接受2个疗程的治疗是极限。作者报告了一例多次复发的三叉神经痛患者,接受了第三个疗程的放射外科治疗,患者疼痛得到成功控制且无额外毒性。对治疗技术的精心关注使得立体定向放射外科能够继续应用于患者。