免疫系统中的多样性：“先入为主的观念”还是“预先形成的观念”？

Diversity in the immune system: "preconceived ideas" or ideas preconceived?

作者信息

Cohn M

出版信息

Biochimie. 1985 Jan;67(1):9-27. doi: 10.1016/s0300-9084(85)80226-1.

Abstract

Two concepts of the evolution and regulation of expression of the combining site repertoire of the immune system, are compared. One view is based on the Associative Recognition Theory as formulated by the author and the other is based on the Idiotype Network Idea as conceived by Jerne. The two concepts are analyzed from the point of view of their logic, internal consistency and factual support.

摘要

本文比较了免疫系统结合位点库表达的进化与调控的两种概念。一种观点基于作者提出的关联识别理论，另一种基于杰尔内提出的独特型网络概念。从逻辑、内部一致性和事实支持的角度对这两种概念进行了分析。