Shuyu Ng Charmaine, Toh Matthias Paul Han Sim, Ko Yu, Yu-Chia Lee Joyce
Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore, Singapore.
Information Management, Central Regional Health Office, National Healthcare Group, Singapore, Singapore; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
PLoS One. 2015 Mar 27;10(3):e0122795. doi: 10.1371/journal.pone.0122795. eCollection 2015.
Due to the chronic nature of diabetes along with their complications, they have been recognised as a major health issue, which results in significant economic burden. This study aims to estimate the direct medical cost associated with type 2 diabetes mellitus (T2DM) in Singapore in 2010 and to examine both the relationship between demographic and clinical state variables with the total estimated expenditure. The National Healthcare Group (NHG) Chronic Disease Management System (CDMS) database was used to identify patients with T2DM in the year 2010. DM-attributable costs estimated included hospitalisations, accident and emergency (A&E) room visits, outpatient physician visits, medications, laboratory tests and allied health services. All charges and unit costs were provided by the NHG. A total of 500 patients with DM were identified for the analyses. The mean annual direct medical cost was found to be $2,034, of which 61% was accounted for by inpatient services, 35% by outpatient services, and 4% by A&E services. Independent determinants of total costs were DM treatments such as the use of insulin only (p<0.001) and the combination of both oral medications and insulin (p=0.047) as well as having complications such as cerebrovascular disease (p<0.001), cardiovascular disease (p=0.002), peripheral vascular disease (p=0.001), and nephropathy (p=0.041). In this study, the cost of DM treatments and DM-related complications were found to be strong determinants of costs. This finding suggests an imperative need to address the economic burden associated with diabetes with urgency and to reorganise resources required to improve healthcare costs.
由于糖尿病及其并发症具有慢性特征,它们已被视为一个重大的健康问题,会导致巨大的经济负担。本研究旨在估算2010年新加坡2型糖尿病(T2DM)的直接医疗成本,并研究人口统计学和临床状态变量与总估算支出之间的关系。使用国家医疗集团(NHG)慢性病管理系统(CDMS)数据库来识别2010年的T2DM患者。估算的糖尿病归因成本包括住院治疗、急诊室就诊、门诊医生诊疗、药物、实验室检查和专职医疗服务。所有费用和单位成本均由NHG提供。总共确定了500名糖尿病患者进行分析。发现平均每年的直接医疗成本为2034美元,其中61%由住院服务产生,35%由门诊服务产生,4%由急诊服务产生。总成本的独立决定因素是糖尿病治疗,如仅使用胰岛素(p<0.001)以及口服药物和胰岛素联合使用(p=0.047),还有并发症,如脑血管疾病(p<0.001)、心血管疾病(p=0.002)、外周血管疾病(p=0.001)和肾病(p=0.041)。在本研究中,发现糖尿病治疗成本和糖尿病相关并发症是成本的重要决定因素。这一发现表明迫切需要紧急应对与糖尿病相关的经济负担,并重新安排所需资源以改善医疗成本。