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塔万猜中心4 - 5岁唇腭裂患者的治疗:相关畸形的患病率及类型

Treatment of 4-5 year old patients with cleft lip and cleft palate in Tawanchai Center: prevalence and type of associated malformations.

作者信息

Pradubwong Suteera, Pongpagatip Sumalee, Pathumwiwatana Pornpen, Kiatchoosakun Pakaphan, Panamonta Manat, Chowchuen Bowornsilp

出版信息

J Med Assoc Thai. 2014 Oct;97 Suppl 10:S1-6.

Abstract

BACKGROUND

Patients with cleft lip/palate may have other associated malformations but the reported prevalence and type of associated malformations varied between different studies.

OBJECTIVE

To report the prevalence and the type of associated malformations in Northeastern Thai patients with cleft lip/palate.

MATERIAL AND METHOD

A retrospective study of 123 cleft lip/palate patients aged 4-5 years was carried out at the Tawanchai Cleft Center, Khon Kaen University during the periodfrom October to December 2011. Data were collected by reviewing the patients medical records.

RESULTS

Seventeen (14%) of the 123patients had associated malformations. Four (21%) of the 19patients with cleft palate, eleven (15%) of the 74 patients with clefts lip and palate, and two (7%) of the 30 patients with cleft lip had associated malformations. The organ systems affected by associated malformations were cardiovascular system (41%), craniofacial anomaly (23%), skeletal system (12%), urogenital system (12%) and central nervous systemn (12%). Atrial septal defect and tetralogy ofFallot were most common associated cardiovascular malformation found.

CONCLUSION

The high prevalence of associated malformationsfound in patients with cleft lip/palate emphasizes the needfor a thorough screening of associated malformations and congenital heart disease ofall cleft lip/palatepatients.

摘要

背景

唇腭裂患者可能伴有其他相关畸形,但不同研究报道的相关畸形患病率及类型有所不同。

目的

报告泰国东北部唇腭裂患者相关畸形的患病率及类型。

材料与方法

2011年10月至12月期间,在孔敬大学塔万猜腭裂中心对123例4 - 5岁唇腭裂患者进行了一项回顾性研究。通过查阅患者病历收集数据。

结果

123例患者中有17例(14%)伴有相关畸形。19例腭裂患者中有4例(214%)、74例唇腭裂患者中有11例(15%)、30例唇裂患者中有2例(7%)伴有相关畸形。受相关畸形影响的器官系统有心血管系统(41%)、颅面畸形(23%)、骨骼系统(12%)、泌尿生殖系统(12%)和中枢神经系统(12%)。房间隔缺损和法洛四联症是最常见的相关心血管畸形。

结论

唇腭裂患者中相关畸形的高患病率强调了对所有唇腭裂患者进行相关畸形和先天性心脏病全面筛查的必要性。

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