重新评估亚临床精索静脉曲张在精液质量受损的不育男性中的作用：一项前瞻性研究。
Reassessing the role of subclinical varicocele in infertile men with impaired semen quality: a prospective study.
作者信息
Cantoro Ubaldo, Polito Massimo, Muzzonigro Giovanni
机构信息
Institute of Urology, A.O. Ospedali Riuniti di Ancona, Ancona, Italy.
Institute of Urology, A.O. Ospedali Riuniti di Ancona, Ancona, Italy.
出版信息
Urology. 2015 Apr;85(4):826-30. doi: 10.1016/j.urology.2015.01.015.
OBJECTIVE
To evaluate the seminal, hormonal, and spontaneous pregnancy outcome after percutaneous embolization of the internal spermatic vein in infertile men with left-sided subclinical varicocele and one or more abnormal semen parameters.
METHODS
A total of 218 patients underwent percutaneous embolization, and 119 patients were included as the observation group. All patients were followed up prospectively for 39.4 ± 6.5 months. Semen parameters and hormonal levels were evaluated before any procedure and 6 months after.
RESULTS
Significant improvement in the mean sperm concentration, total motility, and lower follicle-stimulating hormone levels was noted in those who underwent varicocele embolization as compared with those not treated. After 39.4 ± 6.5 months, pregnancy rates were 46.3% for the treated group and 11.8% for the control group (P = .011).
CONCLUSION
In infertile men, small varicoceles, even subclinical ones, should be identified and treated.
目的
评估左侧亚临床精索静脉曲张且有一项或多项精液参数异常的不育男性经皮精索内静脉栓塞术后的精液、激素及自然妊娠结局。
方法
共有218例患者接受经皮栓塞治疗，119例患者纳入观察组。所有患者均进行前瞻性随访39.4±6.5个月。在任何治疗前及治疗后6个月评估精液参数和激素水平。
结果
与未治疗者相比，接受精索静脉曲张栓塞术者的平均精子浓度、总活力及较低的促卵泡生成素水平有显著改善。在39.4±6.5个月后，治疗组的妊娠率为46.3%，对照组为11.8%（P = 0.011）。
结论
在不育男性中，应识别并治疗小型精索静脉曲张，即使是亚临床型。
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