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精索静脉曲张:治还是不治?

Varicocele: To Treat or Not to Treat?

作者信息

Franco Antonio, Proietti Flavia, Palombi Veronica, Savarese Gabriele, Guidotti Michele, Leonardo Costantino, Ferro Fabio, Manna Claudio, Franco Giorgio

机构信息

Department of Urology, Sant'Andrea Hospital, "Sapienza" University of Rome, 00185 Rome, Italy.

Department of Maternal and Child Health and Urological Sciences, Policlinico Umberto I, "Sapienza" University of Rome, 00185 Rome, Italy.

出版信息

J Clin Med. 2023 Jun 15;12(12):4062. doi: 10.3390/jcm12124062.

DOI:10.3390/jcm12124062
PMID:37373755
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10299325/
Abstract

Varicocele treatment in infertility still remains controversial. It is clear, in fact, that in many patients, varicocele has no impact on fertility. Recent scientific evidence demonstrated that varicocele treatment is beneficial in improving semen parameters and pregnancy rate when an appropriate selection of patients is made. The purpose of treating varicocele in adults is mainly to improve current fertility status. On the other hand, the goal of treatment in adolescents is to prevent testicular injury and maintain testicular function for future fertility. Hence, the key to the success of varicocele treatment seems to be a correct indication. The aim of this study is to review and summarize current evidence in managing varicocele treatment focusing on the controversies regarding surgical indications in adolescent and adult patients, and in other specific situations such as azoospermia, bilateral or subclinical varicocele, and prior to ART.

摘要

精索静脉曲张在不育症治疗中仍然存在争议。事实上,很明显,在许多患者中,精索静脉曲张对生育能力没有影响。最近的科学证据表明,在进行适当的患者选择时,精索静脉曲张治疗有助于改善精液参数和提高妊娠率。治疗成人精索静脉曲张的主要目的是改善当前的生育状况。另一方面,青少年治疗的目标是预防睾丸损伤并维持睾丸功能以保障未来的生育能力。因此,精索静脉曲张治疗成功的关键似乎在于正确的适应症。本研究的目的是回顾和总结当前精索静脉曲张治疗管理方面的证据,重点关注青少年和成年患者手术适应症的争议,以及其他特定情况,如无精子症、双侧或亚临床精索静脉曲张以及辅助生殖技术之前的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17e4/10299325/ae91f172a8ee/jcm-12-04062-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17e4/10299325/7f60aa3ce6b6/jcm-12-04062-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17e4/10299325/ae91f172a8ee/jcm-12-04062-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17e4/10299325/7f60aa3ce6b6/jcm-12-04062-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17e4/10299325/ae91f172a8ee/jcm-12-04062-g002.jpg

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Controversy and Consensus on the Management of Elevated Sperm DNA Fragmentation in Male Infertility: A Global Survey, Current Guidelines, and Expert Recommendations.男性不育症中精子DNA碎片化升高管理的争议与共识:一项全球调查、现行指南及专家建议
World J Mens Health. 2023 Oct;41(4):809-847. doi: 10.5534/wjmh.230008. Epub 2023 Apr 20.
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Radiation Exposure and Surgical Outcomes after Antegrade Sclerotherapy for the Treatment of Varicocele in the Paediatric Population: A Single Centre Experience.小儿精索静脉曲张顺行硬化治疗后的辐射暴露与手术结果:单中心经验
J Clin Med. 2023 Jan 18;12(3):755. doi: 10.3390/jcm12030755.
3
心房颤动患者新发心力衰竭的预防:药物治疗的作用
Am J Cardiovasc Drugs. 2025 Mar;25(2):147-155. doi: 10.1007/s40256-024-00703-y. Epub 2024 Nov 24.
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Varicocele and Interventional Radiology: A Comprehensive Case Study on Diagnosis, Therapeutic Intervention, and Implications for Reproductive Health.精索静脉曲张与介入放射学:关于诊断、治疗干预及对生殖健康影响的综合案例研究
J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2995-S2998. doi: 10.4103/jpbs.jpbs_156_24. Epub 2024 May 29.
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Impact of Varicocele Repair on Assisted Reproductive Technique Outcomes in Infertile Men: A Systematic Review and Meta-Analysis.精索静脉曲张修复术对不育男性辅助生殖技术结局的影响:一项系统评价和荟萃分析
World J Mens Health. 2025 Apr;43(2):344-358. doi: 10.5534/wjmh.240132. Epub 2024 Sep 12.
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Pathological and vascular changes in the rat testiсle after experimental trauma.实验性创伤后大鼠睾丸的病理及血管变化
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